
Mom and Baby Beat 1-in-a-Million Odds to Survive the ‘Rarest of Pregnancies’

The brain rewires itself for motherhood. We now know more about how
Some of the strongest parental instincts happen without conscious thought. The urge to check on a sleeping baby. To stay close. To pick them up when they cry.
Becoming a mother also brings about an extraordinary shift in priorities. As the late British psychotherapist and author Naomi Stadlen wrote, “motherhood can be relentless. The dependency, the need, the constant pull of being someone’s entire world…”
For all mammals, raising young demands enormous time, energy and resources, requiring mothers to place their offspring’s needs ahead of almost everything else.
So just how precisely does the brain make that shift? Our newly published research sought to answer that question.
Using studies in mice, we identified part of the brain circuitry that drives a mother’s urge to interact with her newborn. We found an essential pathway linking a hormone-sensing region of the brain to its reward network.
Activated by the pregnancy hormone placental lactogen and the milk-production hormone prolactin, this pathway helps make caring for a newborn rewarding rather than simply necessary. Remarkably, we were even able to switch that drive on and off experimentally.
Observing a mother’s brain
We focused on a brain region called the medial preoptic area, known for decades to be a key controller of parenting behaviours. Many of its neurons carry receptors for placental lactogen and prolactin.
In earlier studies, we showed that mice without these receptors in this region were unable to care for their offspring after birth. What remained unclear was exactly how these neurons helped drive parenting behaviour.
Using specialised neuroscience techniques to observe these neurons in living mice, we found they became highly active when females came into close contact with pups. The response was much stronger in mothers than in females that had never given birth, with the biggest surge occurring at the very first meeting.
We then traced where these neurons send their signals. A subset of these neurons connect directly to the brain’s reward system, triggering the release of dopamine – the neurochemical that helps make experiences feel rewarding. Recent advances in neuroscience allowed us to watch dopamine being released in real time as mice interacted with their pups.
When we artificially activated this pathway, female mice that had never given birth behaved much more like new mothers. Faced with a barrier separating them from newborn pups, they climbed over it more quickly and repeatedly returned to the pups.
Interestingly, when we blocked the pathway, the opposite happened. Mice no longer showed the normal dopamine surge when meeting the pups and were slower to engage with them. Removing prolactin receptors from the pathway also reduced mother–pup interactions, while leaving other aspects of maternal care largely unchanged.
These new insights help explain why caring for a newborn becomes such a powerful priority after birth. Prolactin acts through this pathway to tune the brain’s reward system, making time with offspring rewarding rather than simply another task.
A peripartum puzzle
Although our work was conducted in mice, the same reward pathways are found in human mothers, with prolactin serving as the key milk-production hormone in all mammals.
The human brain undergoes huge and long-lasting changes during pregnancy, yet very little neuroscience research has focused on females – and even less has looked at how pregnancy causes changes in the brain.
The Ministry of Health estimates that 12–18% of New Zealand women experience depression, anxiety or other mental health conditions during pregnancy or after birth.
The World Health Organisation reports that globally, about 10% of pregnant women and 13% of women who have just given birth experience a mental disorder, primarily depression. In developing countries, this rate is even higher.
Yet there are few treatments that target the biological changes driving these disorders.
Our research aims to understand how the brain adapts during pregnancy and early motherhood to support healthy mood, with the goal of developing better ways to prevent and treat poor peripartum mental health.
We also hope this work will help reduce the stigma faced by parents who struggle to bond with their baby. Rather than personal failing, difficulties with bonding may reflect brain pathways that have not adapted as expected.
Given the profound changes the brain undergoes during pregnancy, it is perhaps unsurprising that this process does not always unfold smoothly. Parents and families deserve better understanding, support and treatment during this critical period.![]()
Rosie Brown, Associate Professor in Physiology, University of Otago; Jenny Clarkson, Research Fellow and Lecturer, Department of Physiology, University of Otago, and Michael Perkinson, Postdoctoral Research Fellow, Department of Physiology, University of Otago
This article is republished from The Conversation under a Creative Commons license. Read the original article.
Couples share 30% of their gut bacteria. Here’s how that may affect health
Conor Meehan, Nottingham Trent University and Janelle Mwerinde, Nottingham Trent University
When living with a partner, you might be sharing more than just the same home, lifestyle and interests. You might also share various microscopic organisms residing on and in you.
This community of microorganisms, which consists of mainly bacteria, viruses and fungi, is known collectively as the human microbiome. The various microbiomes found throughout the body all play an important role in health.
From birth, the human microbiome is shaped by our interactions with our mother, who introduces diverse microorganisms that build our immune and digestive systems. As we get older, social interactions with our close community continue influencing this delicate ecosystem.
The people we live with have huge influence on what microbes we have in our microbiome. In fact, it’s thought that partners share around 30% of their resident microbes in the gut alone.
But it isn’t just the microbes in your gut that may be similar to your partner. The microbes in many other parts of the body may also be shared with your loved one – and this could potentially affect your health.
Gut microbiome
Diet and lifestyle are thought to have the greatest influence on the gut microbiome’s make-up. But studies on couples have found that living with your partner can also influence the microbiome.
Couples living together may share 13% to 30% of their gut bacteria. This was true even when diet (which many couples share) was factored out. Research also shows that couples who live together have greater microbial diversity compared to people who live alone.
This is good news for couples who co-habitate, as a more diverse gut microbiome is correlated with lower risk of irritable bowel syndrome, cardiovascular diseases and potentially high blood sugar.
But it might not all be good news. Research shows that some of the bacterial species couples share can have varying effects on health.
Take the bacteria from the Ruminococcus family. While some species of Ruminoccocus benefit health, others have been linked to negative health outcomes, including diabetes and irritable bowel syndrome.
So these bacteria may not always offer the same benefits in different demographics. This highlights the complexity of resident gut bacteria and their health impacts.
Oral microbiome
Sharing an oral microbiome with our partners might seem obvious considering we regularly exchange saliva when we kiss. A ten-second kiss alone can exchange up to 80 million bacteria. The more kisses a couple shares, the more shared salivary bacteria they will have.
Although most of these bacteria will quickly pass through our mouth and into our gut when we swallow saliva, research show that couples actually share many of the same longer-term tongue microbes that form the foundation of the oral microbiome. Research even suggests that 38% of the oral microbiome is shared in couples living together – compared to only 3% in couples who don’t live together.
Sharing this proportion of your oral microbiome could have many potential health effects.
A healthy oral microbiome is important for protecting against tooth decay and it has anti-inflammatory properties. Some researchers also suggest the oral microbiome’s health effects may extend as far as the gut and nervous system.
But some of the bacteria that couples tend to share may also have potentially harmful health effects.
Couples are more likely to have similar numbers of the bacteria Neisseria in their gut compared to single people. Neisseria can reside in the mouth for long periods of without causing disease.
So while you may want to avoid kissing someone when they’re poorly for obvious reasons, it turns out that a kiss even when you’re healthy can transfer all sorts of bacteria between the two of you.
More research is needed to really understand what overall effect sharing these bacteria with your partner has on health.
Skin microbiome
The skin microbiome is the most unique and personalised microbiome, tailored to each person. It’s even sometimes referred to as our microbial fingerprint.
Being the most exposed microbiome, the skin microbiome has evolved to be adaptable to external factors such as the climate and cosmetic products. No matter what, these bacteria work hard to remain at an equilibrium.
Close contact with our partners – and even pets – has a huge influence on what bacteria live on our skin. After comparing the gut and oral microbiome, researchers found the skin microbiome to be the most similar among couples.
It isn’t just the bacteria on your arms or hands that are shared, either. Research shows that couples shared 35% of the bacteria living on their feet, and around 17.5% of the bacteria on their eyelids.
You may not even need to touch your partner to have the same skin bacteria as them. Factors such as sleeping in the same bed and walking on similar surfaces are thought to explain why such a large proportion of our skin microbiome is similar.
This is because humans naturally shed bacteria in a similar way as dogs shed fur. We leave traces of our bacteria on everything we touch – and we also easily pick up bacteria from our environments.
The shared effect of living together on the skin microbiome is so great that researchers were able to use computer models to accurately predict 86% of cohabiting couples based off of their individual bacterial samples alone.
But while it’s clear that couples share much of the same skin microbiome, the health effect that this has is not currently known.
While sharing bacteria with your partner may sound alarming, there’s often no cause for concern. Bacteria teach our bodies how to fight infections, they help us digest foods and even produce key nutrients. The bacteria we share with our partners are often harmless and sometimes benefit our health rather than hindering it.![]()
Conor Meehan, Associate Professor of Microbial Bioinformatics, Nottingham Trent University and Janelle Mwerinde, PhD Candidate, Skin Microbiology, Nottingham Trent University
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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Why Should You Breastfeed Your Baby?
- Providing all necessary nutrients for the baby’s healthy physical development, including vitamin D, iron, and zinc
- Preventing infections and serious health conditions, both during infancy and later in life
- Reducing a mother’s risk of conditions such as cancer, type 2 diabetes, and high blood pressure
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Women More Attracted To Men In Red
It's a symbol of courage and sacrifice, of sin and sexuality, of power and passion -- and now new research demonstrates that the color red makes men more alluring to women. In the United States, England, Germany and China, women found men more appealing when they were either pictured wearing red or framed in red, compared with other colors. The finding is reported in the August issue of the Journal of Experimental Psychology: General, published by the American Psychological Association. "Red is typically thought of as a sexy color for women only," said Andrew Elliot, PhD, of the University of Rochester and University of Munich. "Our findings suggest that the link between red and sex also applies to men." Twenty-five men and 32 women briefly viewed a black-and-white photo of a Caucasian man in a polo shirt, surrounded by a red or white matte. Using a nine-point scale, they answered three questions: "How attractive do you think this person is?" "How pleasant is this person to look at?" and "If I were to meet the person in this picture face to face, I would think he is attractive." Red warmed up women only. Women who looked at a man surrounded by red or white rated the man surrounded by red a little over one point higher on a nine-point scale of attractiveness, a statistically significant bump. Another experiment featured a man in a color photo, dressed in either a red or a green shirt. A pool of 55 women rated the man in red as significantly more attractive -- on average, nearly one point higher on the same nine-point scale. They also thought he was more desirable, according to a second, five-item measure that asked viewers to rate, for example, the likelihood that they'd want to have sex with him. Although red means different things in different cultures, the finding of women (but not men) drawn to men in red was consistent across countries. And it's true about red power ties: Women in a follow-up study perceived men wearing red T-shirts to be significantly more likely to be high in status than men wearing blue T-shirts, in addition to the men in red seeming more generally and sexually attractive. Five smaller studies (20-38 participants) comparing women's responses to men in red or gray, including their sense of the men's status, established a chain of evidence that red may enhance sexual attractiveness because red is a status symbol, according to the authors. The power of red holds throughout the primate world. Female primates (including women) are "extremely adept at detecting and decoding blood flow changes in the face," the authors wrote, "and women have been shown to be more sensitive to the perception of red stimuli than are men." Are men aware that red may work in the bedroom as well as the boardroom? The authors suggest red might make men more likely to strut their stuff. "A man who wears red may feel dominant," they added, "which influences his self-confidence and behavior and in turn may impress women." The American Psychological Association, in Washington, D.C., is the largest scientific and professional organization representing psychology in the United States and is the world's largest association of psychologists. APA's membership includes more than 152,000 researchers, educators, clinicians, consultants and students. Through its divisions in 54 subfields of psychology and affiliations with 60 state, territorial and Canadian provincial associations, APA works to advance psychology as a science, as a profession and as a means of promoting health, education and human welfare. Contacts and sources: Public Affairs Office, American Psychological Association, Journal of Experimental Psychology: General, Article: "Red, Rank, and Romance in Women Viewing Men," Andrew Elliot, PhD, University of Rochester and University of Munich; Daniela Niesta Kayser, PhD, University of Rochester; Tobias G. Greitemeyer, PhD, University of Innsbruck; Stephanie Lichtenfield, PhD, University of Munich; Richard H. Gramzow, PhD, University of Southampton; Markus A. Maier, PhD, University of Munich; Huijun Liu, PhD, Tianjin Medical University; Journal of Experimental Psychology: General, Vol. 139, No. 3. (Full text of the article is available from the APA Public Affairs Office and at http://www.apa.org/pubs/journals/releases/xge-139-3-399.pdf), Source: ArticleWorld’s most lifelike bionic hand will transform the lives of amputees
A congenital amputee from London has become the first user in the UK to be fitted with a new prosthetic hand that launches this week and sets a new benchmark in small myoelectric hands.
Why do we cry?

Ad Vingerhoets is probably the only “crying professor” (from the University of Tilburg). Why do people cry? He says that crying is not so much about feeling sad, but about feeling hopeless and powerless or other feelings like altruism, self sacrifice etc. He says women and children mostly cry with someone else while men prefer to cry alone. In Northern, colder countries, people cry more because in warmer countries there are more social conventions. The less testosterone, the more easily men cry. Source: Article, Image: flickr.com
Lab engineered vaginas implanted in patients in US
Scientists reported today the first human recipients of laboratory-grown vaginal organs. A research team led by Anthony Atala, M.D., director of Wake Forest Baptist Medical Center’s Institute for Regenerative Medicine, describes in the Lancet long-term success in four teenage girls who received vaginal organs that were engineered with their own cells. “This pilot study is the first to demonstrate that vaginal organs can be constructed in the lab and used successfully in humans,” said Atala. “This may represent a new option for patients who require vaginal reconstructive surgeries. In addition, this study is one more example of how regenerative medicine strategies can be applied to a variety of tissues and organs.” The girls in the study were born with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, a rare genetic condition in which the vagina and uterus are underdeveloped or absent. The treatment could also potentially be applied to patients with vaginal cancer or injuries, according to the researchers. The girls were between 13 and 18 years old at the time of the surgeries, which were performed between June 2005 and October 2008. Data from annual follow-up visits show that even up to eight years after the surgeries, the organs had normal function. “Tissue biopsies, MRI scans and internal exams using magnification all showed that the engineered vaginas were similar in makeup and function to native tissue, said Atlantida-Raya Rivera, lead author and director of the HIMFG Tissue Engineering Laboratory at the MRKH in Mexico City, where the surgeries were performed. In addition, the patients’ responses to a Female Sexual Function Index questionnaire showed they had normal sexual function after the treatment, including desire and pain-free intercourse. The organ structures were engineered using muscle and epithelial cells (the cells that line the body’s cavities) from a small biopsy of each patient’s external genitals. In a Good Manufacturing Practices facility, the cells were extracted from the tissues, expanded and then placed on a biodegradable material that was hand-sewn into a vagina-like shape. These scaffolds were tailor-made to fit each patient. About five to six weeks after the biopsy, surgeons created a canal in the patient’s pelvis and sutured the scaffold to reproductive structures. Previous laboratory and clinical research in Atala’s lab has shown that once cell-seeded scaffolds are implanted in the body, nerves and blood vessels form and the cells expand and form tissue. At the same time the scaffolding material is being absorbed by the body, the cells lay down materials to form a permanent support structure – gradually replacing the engineered scaffold with a new organ. Followup testing on the lab-engineered vaginas showed the margin between native tissue and the engineered segments was indistinguishable and that the scaffold had developed into tri-layer vaginal tissue. Current treatments for MRHK syndrome include dilation of existing tissue or reconstructive surgery to create new vaginal tissue. A variety of materials can be used to surgically construct a new vagina – from skin grafts to tissue that lines the abdominal cavity. However, these substitutes often lack a normal muscle layer and some patients can develop a narrowing or contracting of the vagina. The researchers say that with conventional treatments, the overall complication rate is as high as 75 percent in pediatric patients, with the need for vaginal dilation due to narrowing being the most common complication. Before beginning the pilot clinical study, Atala’s team evaluated lab-built vaginas in mice and rabbits beginning in the early 1990s. In these studies, scientists discovered the importance of using cells on the scaffolds. Atala’s team used a similar approach to engineer replacement bladders that were implanted in nine children beginning in 1998, becoming the first in the world to implant laboratory-grown organs in humans. The team has also successfully implanted lab-engineered urine tubes (urethras) into young boys. The team said the current study is limited because of its size, and that it will be important to gain further clinical experience with the technique and to compare it with established surgical procedures. Co-researchers were James J. Yoo, M.D., Ph.D., and Shay Soker, Ph.D., Wake Forest Baptist, and Diego R. Esquiliano M.D., Reyna Fierro-Pastrana P.hD., Esther Lopez-Bayghen Ph.D., Pedro Valencia M.D., and Ricardo Ordorica-Flores, M.D.,Children’s Hospital Mexico Federico Gomez Metropolitan Autonomous University, Mexico. Source: Article,
How to make goat milk lotion
BY THE GOAT CHEESE LADY: I tend to do things at the last minute — I believe they call it
- 10.2 oz water
- 10.2 oz goat milk
- 1.2 oz emulsifying wax
- 3.7 oz oils (use any assortment of oils you like, as long as the total weight is 3.7 oz)
- 1.2 oz shea butter
- .3 oz optiphen or germaben II
- Heat oils and butters until melted. Add emulsifying wax and heat until melted.
- Combine milk and water and heat to 80-100 degrees.
- Combine oil, butters, wax with milk and water mixture.
- Mix with an emersion blender until mixture thickens, 2-5 minutes.
- Add optiphen or germaben II (preservatives), mix 1 minute. Mixture will thin again.
- Pour mixture into containers and let cool. The lotion will thicken again at room temperature.
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