Cataract Surgery Restores Sight for 54-Year-Old Chimpanzee–the First Such Procedure at Chimp Haven

Pierre the Chimp recovering from cataract surgery – credit, Chimp Haven, supplied

After becoming completely blind from cataracts, a 54-year-old chimpanzee named Pierre is seeing again following a successful surgery at Chimp Haven, the world’s largest chimpanzee sanctuary.

The procedure, the first cataract surgery performed for a resident at Chimp Haven, restored functional sight and allowed Pierre to quickly begin reconnecting with the people, chimpanzees, and activities familiar to him.

As Pierre’s vision had declined, caregivers adapted his daily routines and environment to help him continue navigating as independently as possible. Staff used sound cues and specialized feeding approaches and added handholds, ladders and other supports to areas Pierre used regularly.

Eventually though, it was agreed that a surgical procedure was necessary, something which would require months of preparation.

In preparation for his recovery and potential post-operative needs, the team used positive reinforcement training to teach Pierre to voluntarily present his eyes for care, including positioning that would allow staff to administer eyedrops and closely monitor his eyes if needed. Pierre learned to participate in this care while he was still blind, helping the team prepare to safely provide treatment without compromising his comfort or welfare.

A board-certified veterinary ophthalmologist, Dr. Kenneth Pierce, performed the procedure to remove cataracts from Pierre’s eyes. The results were noticeable almost immediately.

Within hours of surgery, he was responding visually to a longtime caregiver, and within days he was reuniting with Jill, one of his closest chimpanzee companions. Pierre was ultimately able to return to his social group earlier than initially expected.

Scenes from Pierre’s surgery – credit, Chimp Haven, supplied

“Pierre’s recovery is a wonderful example of what individualized care can look like for an aging chimpanzee,” said Dr. DaShaunté Coleman, veterinarian at Chimp Haven.

“The surgery itself was only one part of the process. Months of preparation and collaboration across our care teams helped ensure Pierre was comfortable participating in any follow-up care that might be needed and gave him the best opportunity for a successful recovery.”

Among the first people Pierre saw was Colony Director Michelle Reininger, who has known and cared for him for more than 25 years.

“Watching Pierre look at me again was something I will never forget,” Reininger said.

As lately as the 1980s, chimpanzees were still widely subjected to medical research trials in the US through captive breeding programs. Ethical debates about this practice became more common as the years went on, while at the same time the National Institutes of Health was required to care for an ever greater number of captive chimps and the complex full-time care they need to thrive.

Varied groups proposed a species-specific sanctuary for chimps of all ages retired from medical research, and in 2000, the Caddo Parish Commission in Northwest Louisiana donated 200 wooded acres of the Eddie D. Jones Nature Park to build the new facility.

Chimp Haven has been providing hundreds of chimpanzees ever since with a large territory to live enriched and fulfilling lives, which includes sophisticated medical care such as what Pierre received.

“Every chimpanzee ages differently, just like people do,” Dr. Coleman said in a statement. “Our goal is to understand what each individual needs and help them remain comfortable, active and connected to their social group as they age.”“In Pierre’s case, months of preparation made it possible for him to receive this specialized care and get back to the routines and relationships that are important to him.” Cataract Surgery Restores Sight for 54-Year-Old Chimpanzee–the First Such Procedure at Chimp Haven
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Woman Can See Again After World’s First Transplant of a Central Retina

Elena with her dog Joe, and Professor Michele Reibaldi – credit, Ospedale Molinette, supplied

From Turin comes a surgical world-first: the simultaneous transplant of a complete human macula, along with the cornea, sclera, and connective tissue, from one of the patient’s eyes to the other.

It allowed a woman blind for several years to immediately gain enough vision to recognize both her son and her faithful canine companion, Joe.

La Stampa, a Turn-based national newspaper, reported that the intervention was lead by the “intuition” of ocular surgeon Professor Michele Reibaldi, who himself described the process as a “complicated marathon,” lasting 6 hours and requiring careful coordination by surgeons, anesthetists, and orderlies.

The patient was 67-year-old Elena, who lost her eyesight in a road incident which completely severed the optic nerve in her left eye. Responsible for transmitting light absorbed and delineated through the eye to the brain, the irreversible damage was not shared by the rest of eye tissues, which remained largely intact.

In an interesting coincidence, the reverse was true for her right eye. While the optic nerve was undamaged, the trauma of the crash destroyed other parts of her eye including the retina, the cornea, and the portion of the eye containing ocular stem cells, rendering any hope of a normal corneal transplant impossible.

In short, there was enough undamaged components between her two eyes to create one that could function. The only problem was that it would require a surgery never done in the history of medicine, a macular transplant. The macula is a small, light-sensitive region at the back of the retina, itself located in the middle of the eyeball, responsible for high-definition sight. The common cause of blindness, macular degeneration, refers to this small tissue.

Elena also needed a new cornea, and the sclera—the white of the eyeball. Professor Reibaldi resolved to salvage those from the left eye and transplant them all to the right eye, in which the ocular nerve was preserved through the crash.

“This procedure represents a new frontier in ocular surgery,” Reibaldi, who practices at the Molinette Hospital in Turn’s City of Health and Science, said according to a translation. “Before today, such a contemporaneous transplant of the anterior eye tissue had occurred just once before, while the central retina has never been possible.”

“Now we will wait and see how well the transplanted retina functions, though early signs are encouraging.”

Follow-ups have confirmed that the tissues have reattached correctly, and that Elena is regaining sight in her right eye.Reibaldi praised the extraordinary collaboration within the team which carried out the procedure, before adding that the biggest prize for them was “the incredible moment in which Elena, opening her eyes, could finally recognize her son and faithful companion in life, Joe the dog.” Woman Can See Again After World’s First Transplant of a Central Retina
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