Scientists Find Answer to Sea Star Population Devastated by Pathogen Along the California Coast

A sunflower sea star – credit, Ed Bierman CC 2.0.For years, a wasting disease has been turning sea stars to goo off the California coast. Scientists now finally know the cause, and are beginning to fight back.Whether it has over 20 arms like the sunflower sea star, or just 5, billions of Pacific sea stars were being wiped out by an unknown assailant.After four years of experiments from a huge collaborative effort led by the Hakai Institute, biologists finally identified the culprit: a kind of bacteria called Vibrio.Devastating to coral, shellfish, and human beings, this strain of Vibrio has been labeled FHCF-3. The scientists determined it was the cause of the epidemic by examining what might be called the sea star’s blood. It doesn’t have blood as we would recognize it, but a circulatory fluid called coelomic fluid.As to what is causing the spread of FHCF-3, ranging from Washington state down to the Baja Peninsula, the scientists point to warming waters.“We have evidence that there is a link between increasing ocean temperatures and this sea star wasting disease epidemic,” said Melanie Prentice, one of the co-authors of the paper published on the discovery in Nature, to CBS News.Sunflower sea stars, one of the species that’s been most affected, are voracious eaters of sea urchins. This slow motion game of lion and gazelle plays...
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US scientists developing single-dose vaccines for HIV, Covid

New Delhi, August 28 (IANS) A team of scientists in the US is working to develop vaccines that can protect against HIV, Covid, and potentially other diseases, with a single dose.The team from MIT and the Scripps Research Institute treated mice with a vaccine that combines two different adjuvants, materials that help stimulate the immune system. They found that the combination helped generate more robust immune responses.The dual-adjuvant vaccine was found to accumulate in the lymph nodes, where white blood cells known as B cells encounter antigens and undergo rapid mutations that generate new antibodies.The vaccine’s antigens remained there for up to a month -- allowing the immune system to build up a much greater number and diversity of antibodies against the HIV protein than the vaccine given alone or with one adjuvant.According to MIT professor J. Christopher Love, the approach may mimic what occurs during a natural infection and could lead to an immune response so strong and broad that vaccines only need to be given once.“It offers the opportunity to engineer new formulations for these types of vaccines across a wide range of different diseases, such as influenza, SARS-CoV-2, or other pandemic outbreaks,” Love said.Separately, Russia’s Covid-19 vaccine maker is also set to develop an mRNA-based HIV vaccine, RIA Novosti, the...
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