AI-powered digital stethoscopes show promise in bridging screening gaps

(Photo: Eko Health, US) IANS

New Delhi, As tuberculosis (TB) continues as the deadliest infectious cause of deaths globally, a new study has shown that artificial intelligence (AI)-enabled digital stethoscopes can help fill critical screening gaps, especially in hard-to-reach areas.

In a commentary published in the journal Med (Cell Press), global experts contended that stethoscopes combined with digital technology and AI can be a better option against the challenges faced in screening programmes, such as under-detection, high cost, and inequitable access.

“AI-enabled digital stethoscopes have demonstrated promising accuracy and feasibility for detecting lung and cardiovascular abnormalities, with promising results in early TB studies. Training and validation in diverse, high-burden settings are essential to explore the potential of this tool further,” said corresponding author Madhukar Pai from McGill University, Canada, along with researchers from the UAE, Germany, and Switzerland.

Despite advancements in screening and diagnostic tools, an estimated 2.7 million people with TB were missed by current screening programmes, as per data from the World Health Organization (WHO). Routine symptom screening is also likely to miss people with asymptomatic or subclinical TB.

While the WHO recently recommended several AI-powered computer-aided detection (CAD) software, as well as ultra-portable radiography hardware, higher operating costs and upfront hardware act as a deterrent.

This particularly appeared difficult in primary care settings and or among pregnant women due to radiation concerns.

At the same time, AI showed significant potential for screening, including applications beyond CAD of TB from radiographs, said the researchers.

“One application of AI for disease screening is to interpret acoustic (sound) biomarkers of disease, with potential to identify sounds that appear nonspecific or are inaudible to the human ear,” they added, while highlighting the potential of AI in detecting and interpreting cough biomarkers and lung auscultation to analyse breath sounds.

Studies from high-TB burden countries, including India, Peru, South Africa, Uganda, and Vietnam, highlighted that AI-enabled auscultation could hold promise as a TB screening and triage tool.

"AI digital stethoscopes may become useful alternatives to imaging-based approaches for TB screening, with the potential to democratise access to care for populations underserved by radiography," the researchers said."Importantly, AI digital stethoscopes offer a scalable, low-cost, and person-centered tool that could bring us closer to reaching TB case finding goals," they added. AI-powered digital stethoscopes show promise in bridging screening gaps | MorungExpress | morungexpress.com
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EV Charging Answer: Quantum Technology Will Cut Time it Takes to Charge Electric Cars to Just 9 Seconds

Institute for Basic Science

Scientists in South Korea have proven that a new technology will cut the time it takes to charge electric cars to just nine seconds, allowing EV owners to ‘fill up’ faster than their gasoline counterparts.

And even those plugging-in at home will have the time slashed from 10 hours to three minutes.

The new device uses the laws of quantum physics to power all of a battery’s cells at once—instead of one at a time—so recharging takes no longer than filling up at the pump.

Electric cars were rarely seen on the roads 10 years ago, but millions are now being sold every year and it has become one of the fastest growing industries, but even the fastest superchargers need around 20 to 40 minutes to power their car.

Scientists at the Institute for Basic Science (IBS) in South Korea have come up with a solution. Co-author Dr. Dario Rosa said the consequences could be far-reaching.

“Quantum charging could go well beyond electric cars and consumer electronics. For example, it may find key uses in future fusion power plants, which require large amounts of energy to be charged and discharged in an instant.”

The concept of a “quantum battery” was first proposed in a seminal paper published by Alicki and Fannes in 2012. It was theorized that quantum resources, such as entanglement, can be used to vastly speed up battery charging.

The researchers used quantum mechanics to model their super fast charging station with calculations of the charging speed showing that a typical electric vehicle with a battery containing around 200 cells would recharge 200 times faster.

Current collective charging is not possible in classical batteries, where the cells are charged in parallel, independently of one another.

“This is particularly exciting as modern large-capacity batteries can contain numerous cells.”

The group went further to provide an explicit way of designing such batteries.

This means charging times could be cut from 10 hours to three minutes at home and from around 30 minutes to just a few seconds at stations.

Co-author Dr Dominik Å afránek said, “Of course, quantum technologies are still in their infancy and there is a long way to go before these methods can be implemented in practice.”

“Research findings such as these, however, create a promising direction and can incentivize the funding agencies and businesses to further invest in these technologies.

“If employed, it is believed that quantum batteries would completely revolutionize the way we use energy and take us a step closer to our sustainable future.”

The findings were published in the February 8 edition of the journal Physical Review Letters. [GNN updated the earlier broken link.] EV Charging Answer: Quantum Technology Will Cut Time it Takes to Charge Electric Cars to Just 9 Seconds
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Multiple Types of Plastic Are Turned into Vinegar Using Sunlight-Powered Process Without Emissions

Waterloo PhD student Wei Wei, who led the research – credit, University of Waterloo, released

Researchers at the University of Waterloo have discovered a way to turn plastic waste into acetic acid, the main ingredient of vinegar, using sunlight.

The breakthrough offers a promising new approach to reducing plastic pollution through photocatalysis, while simultaneously creating a useful, value-added chemical product through a process inspired by nature.

“Our goal was to solve the plastic pollution challenge by converting microplastic waste into high-value products using sunlight,” said Dr. Yimin Wu, a professor of mechanical and mechatronics engineering at the University of Waterloo, Canada.

Plastic waste, notably microplastics, has been found across many of the planet’s ecosystems, raising concerns about threats to terrestrial and marine life as well as human health. Plastic recycling rates remain low around the globe.

To tackle this problem, the team developed a bio-inspired photocatalysis process using iron atoms embedded in carbon nitride, a way that certain types of fungi break down organic matter using enzymes.

When exposed to sunlight, the material drives a series of chemical reactions that transform plastic polymers into acetic acid with high selectivity. The reaction takes place in water, making it particularly relevant for addressing plastic pollution in aquatic environments.

Acetic acid is widely used in food production, chemical manufacturing and energy applications. The study shows it can be produced from common plastic wastes, including PVC, PP, PE and PET, and remains effective across mixed plastic compositions.

This makes the approach well suited to real-world waste streams, offering a promising alternative to plastic incineration, and could support more circular approaches to material use while providing a new strategy for upcycling plastics.

“Both from a business and societal perspective, the financial and economic benefits associated with this innovation seem promising,” said Roy Brouwer, executive director of the Water Institute and a coauthor of the article supporting the techno-economic analysis.

“This method allows abundant and free solar energy to break down plastic pollution without adding extra carbon dioxide to the atmosphere,” Wu adds.

The findings also point to new possibilities for addressing microplastics directly. Because the process degrades plastics at the chemical level, it could help prevent the accumulation of microplastics in water systems.While still at the laboratory stage, the team envisions that this approach could be adapted for scalable, solar-driven recycling and environmental cleanup and the photocatalytic upcycling system can be further enhanced through strategic engineering of the materials and manufacturing processes. Multiple Types of Plastic Are Turned into Vinegar Using Sunlight-Powered Process Without Emissions
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AI could help us more accurately screen for breast cancer – new research

At least 20,000 Australian women are diagnosed with breast cancer each year. And more than 3,300 die from the disease.

To save women’s lives, we need to detect breast cancer early. Breast screening, which halves women’s risk of dying from breast cancer, is key to that.

A new Australian study published today in The Lancet Digital Health suggests AI could help improve how we screen for breast cancer.

How do we currently screen for breast cancer?

Since 1992, Australia has offered free breast X-rays, known as mammograms, every two years to women aged between 50 and 74. Just over half of eligible women participate.

Of the women found to have cancer, about 25% are diagnosed between the biennial screens. These “interval cancers” are often aggressive and, unfortunately, more likely to be fatal.

In some cases, a more sensitive screening test may have detected them earlier.

The role of AI

Australia’s BreastScreen program was established in response to several major clinical trials conducted between the 1960s and 1980s. The screening technology used by the program has not substantially changed since then.

Researchers are now exploring risk-adjusted screening, which tailors screening to women based on their risk, as a way to detect more cancers earlier. This may include programs offering different technologies for women at higher risk of developing breast cancer.

Currently, we generally assess cancer risk via questionnaires that help identify if a woman has any risk factors associated with breast cancer.

One risk factor is breast density which refers to how much glandular tissue is in the breast. As well as being a risk factor for breast cancer, the higher a woman’s breast density, the harder it is to detect cancer on a mammogram.

We can also use one-off genetic testing to identify women with a higher lifetime risk of developing breast cancer. This involves looking for high-risk gene mutations such as BRCA1 and BRCA2, which are associated with increased breast and ovarian cancer risk. Genetic testing can also help us estimate a person’s lifetime risk of developing breast cancer.

More recently, researchers have been investigating artificial intelligence (AI) as a new approach to assess breast cancer risk. A new Australian study, published in The Lancet Digital Health today, focused on a specific AI tool known as BRAIx.

What did the study involve? And what did it find?

This study used an AI tool, known as BRAIx, trained using BreastScreen Australia data to help radiologists assess mammograms.

The study assessed how well BRAIx predicted women’s risk of developing breast cancer in the next four years, among women who had a clear mammogram.

Of the 95,823 Australian women assessed, 1.1% (1,098) had developed breast cancer in the four years after they received a clear mammogram. Of the 4,430 Swedish women assessed, 6.9% had developed breast cancer within two years of a clear screen.

The study findings show that BRAIx scores were very useful for identifying women who were more likely to develop cancer one to two years after having a clear screen. Findings from the Australian dataset suggest BRAIx scores identified cancers found three to four years later, but with less accuracy.

These findings suggest BRAIx could help identify women who might benefit from additional tests. This may include an MRI (which uses a magnetic field to produce images of organs and tissue) or contrast-enhanced mammography (which uses an iodine dye to improve the visibility of a regular mammogram).

These findings reinforce a 2024 Swedish study that used an AI-based risk assessment to select women for additional testing. The researchers referred 7% of women to have a follow-up MRI, and 6.5% of were found to have cancers missed by mammograms.

Does the study have any limitations?

As with most studies, yes. Here are two.

  • it’s difficult to compare BRAIx to genetic testing. This is because BRAIx is trained to find missed or emerging cancers over a four year period. In contrast, genetic testing identifies a person’s risk of developing cancer over their lifetime

  • it might not use the best breast density data. This study found BRAIx more accurately predicts breast cancer risk compared to assessments based on breast density. But this breast density data was collected using a different tool to those used by the Breastscreen program. So this finding should be interpreted carefully.

So, where to from here?

The study adds to a growing body of evidence that AI risk assessment could help breast screening programs find cancers earlier.

BRAIx is now being trialled as part of the BreastScreen Victoria program, to help read mammograms. And other states are already using and evaluating different AI tools for reading mammograms.

So it may be time for Australia to conduct a national, independent review of these new tools. As part of a more risk-adjusted approach to breast screening, they could save lives.The Conversation

Carolyn Nickson, Principal Research Fellow, Cancer Elimination Collaboration, University of Sydney; The University of Melbourne and Bruce Mann, Professor of Surgery, Specialist Breast Surgeon, The University of Melbourne

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Wildlife Poachers to Be Targeted Using State of the Art AI Listening Technology

A photo of a male forest elephant captured near the site where some of the gunshot recordings were taken – credit, Anahita Verahrami / SWNS

Wildlife poachers can now be located and arrested across the central African forests thanks to state-of-the-art AI listening technology.

A network of microphones has been deployed across the rainforests to detect gunshots from illegal poaching of elephants and other animals, and American scientists are using AI to ensure the network can distinguish gunshots over the din of the jungle environment.

The web of acoustic sensors was deployed in Gabon, Congo, and Cameroon, creating the possibility of real-time alerts to the sounds of gun-based poaching.

But the belly of the rainforest is loud, and scientists say sorting through a constant influx of sound data is computationally demanding. Detectors can distinguish a loud bang from the whistles, chirps, and rasps of birds and bugs, but they often confuse the sounds of branches cracking or trees falling with gunshot noises, resulting in a high percentage of false positives.

Project leader Naveen Dhar at Center for Conservation Bioacoustics at Cornell University aimed to develop a lightweight gunshot detection neural network that can accompany sensors and process signals in real-time to minimize false positives.

He worked alongside colleagues at the Elephant Listening Project to create a model that will work through autonomous recording units (ARUs), which are power-efficient microphones that capture continuous, long-term soundscapes.

“The proposed system utilizes a web of ARUs deployed across the forest, each performing real-time detection, with a central hub that handles more complex processing.”

An initial scan filters all audio for “gunshot likely” signals and sends them to the ARU’s microprocessor, where the lightweight gunshot detection model lives.

If confirmed as a gunshot by the microprocessor, the ARU passes the information to the central hub, initiating data collection from other devices in the web.


By determining if other sensors also hear a “gunshot likely” noise, the central hub then decides whether the event was a true gunshot or a potential false positive.

If it determines a true positive, the central hub collates audio files from each sensor, allowing it to pinpoint the location of the gunshot and alert rangers on the ground with coordinates for immediate poaching intervention.

“Down the road, the device can be used as a tool for rangers and conservation managers, providing accurate and verifiable alerts for on-the-ground intervention along with low-latency data on the spatiotemporal trends of poachers,” Dhar said.

He plans to expand the model to detect the type of gun that fires each gunshot and other human activities, such as chainsaws or trucks, before field-testing the system, which is currently under development.

“I hope the device can coalesce with Internet of Things infrastructure innovations and cost reduction of materials to produce a low-cost, open-source framework for real-time detection usable in any part of the globe.”He is due to present his findings at a joint meeting of the Acoustical Society of America and Acoustical Society of Japan, in Honolulu, Hawaii. Wildlife Poachers to Be Targeted Using State of the Art AI Listening Technology:
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Scientists Develop Biodegradable Smart Textile–A Big Leap Forward for Eco-Friendly Wearable Technology

Flexible inkjet printed E-textile – Credit: Marzia Dulal

Wearable electronic textiles can be both sustainable and biodegradable, shows a new study.

A research team led by the University of Southampton and UWE Bristol in the UK tested a new sustainable approach for fully inkjet-printed, eco-friendly e-textiles.

Named SWEET—for Smart, Wearable, and Eco-friendly Electronic Textiles—the new ‘fabric’ was described in findings published in the journal Energy and Environmental Materials.


E-textiles are those with embedded electrical components, such as sensors, batteries or lights. They might be used in fashion, for performance sportswear, or for medical purposes as garments that monitor people’s vital signs.

Such textiles need to be durable, safe to wear and comfortable, but also, in an industry which is increasingly concerned with clothing waste, they need to be kind to the environment when no longer required.

“Integrating electrical components into conventional textiles complicates the recycling of the material because it often contains metals, such as silver, that don’t easily biodegrade,” explained Professor Nazmul Karim at the University of Southampton.


“Our eco-friendly approach for selecting sustainable materials and manufacturing overcomes this, enabling the fabric to decompose when it is disposed of.”

The team’s design has three layers, a sensing layer, a layer to interface with the sensors and a base fabric. It uses a textile called Tencel for the base, which is made from renewable wood and is biodegradable.

The active electronics in the design are made from graphene, along with a polymer called PEDOT: PSS. These conductive materials are precision inkjet-printed onto the fabric.

The research team, which included members from the universities of Exeter, Cambridge, Leeds, and Bath, tested samples of the material for continuous monitoring of heart rates. Five volunteers were connected to monitoring equipment, attached to gloves worn by the participants. Results confirmed the material can effectively and reliably measure both heart rate and temperature at the industry standard level.

Gloves with e-textile sensors monitoring heart rate – Credit: Marzia Dulal

“Achieving reliable, industry-standard monitoring with eco-friendly materials is a significant milestone,” said Dr. Shaila Afroj, an Associate Professor of Sustainable Materials from the University of Exeter and a co-author of the study. “It demonstrates that sustainability doesn’t have to come at the cost of functionality, especially in critical applications like healthcare.”

The project team then buried the e-textiles in soil to measure its biodegradable properties.

After four months, the fabric had lost 48 percent of its weight and 98 percent of its strength, suggesting relatively rapid and also effective decomposition.

Furthermore, a life cycle assessment revealed the graphene-based electrodes had up to 40 times less impact on the environment than standard electrodes.

Four strips in a variety of decomposed states, during four months of decomposition – Credit: Marzia Dulal

Marzia Dulal from UWE Bristol, the first author of the study, highlighted the environmental impact: “Our life cycle analysis shows that graphene-based e-textiles have a fraction of the environmental footprint compared to traditional electronics. This makes them a more responsible choice for industries looking to reduce their ecological impact.”

The ink-jet printing process is also a more sustainable approach for e-textile fabrications, depositing exact numbers of functional materials on textiles as needed, with almost no material waste and less use of water and energy than conventional screen printing.“These materials will become increasingly more important in our lives,” concluded Prof. Karim, who hopes to move forward with the team to design wearable garments made from SWEET, particularly in the area of early detection and prevention of heart diseases. Scientists Develop Biodegradable Smart Textile–A Big Leap Forward for Eco-Friendly Wearable Technology
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Samsung's 600-Mile-Range Batteries That Charge in 9 Minutes Ready for Production/Sale Next Year

A mock-up design of Samsung SDI’s solid-state battery – credit, Samsung, released

In late October, Samsung announced that it was preparing to take its long-anticipated solid-state batteries to market with a trilateral agreement between itself, BMW, and American battery expert Solid Power.

It was January of last year that industry outlets began to get some of the promises that all-solid-state batteries (ASSBs) developed by Samsung SDI would bring. With an energy density of 500 watt-hours per kilogram, they’re twice as dense as conventional lithium-ion batteries.

Samsung claimed they were smaller, lighter, and safer, capable of driving 600 miles, and charging with
in 9 minutes. Typically, a lithium-ion battery pack in a modern EV charges from 10% to 80% in around 45 minutes, and has a limit of around 300 miles of range.

“Samsung SDI’s preparations for mass-producing next-generation products of various form factors such as an all-solid-state battery are well underway as we are set to lead the global battery market with our unrivaled ‘super-gap’ technology,” said Samsung SDI CEO Yoon-ho Choi.

ASSB cells use solid electrolyte instead of liquid electrolyte found in a lithium-ion battery. They offer superior safety, as they aren’t flammable, and last for 20 years, or 2,000 charge-discharges, equating to 1.2 million miles.

Under the trilateral agreement, Samsung will supply ASSB cells featuring the solid electrolyte developed by Solid Power to the German automotive group BMW, which will then develop modules and packs for ASSB cells to fit into their next-generation evaluation vehicles, expected in late 2026.

Metal Tech News reported in January that ASSBs will also debut in some smaller Samsung devices during 2026, including the Galaxy Ring fitness tracker, as a way of testing the new power supplies in the real world before incorporating them into smartphones, laptops, and other devices.Samsung’s ASSBs use a silver-carbon layer as the anode and a nickel-manganese-cobalt material for the cathode. Silver is not only the most electrically conductive metal available, it’s also substantially more plentiful in the Earth’s crust than lithium. Samsung's 600-Mile-Range Batteries That Charge in 9 Minutes Ready for Production/Sale Next Year
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AI tool can simulate complex fusion plasma in seconds

(Image: UKAEA)

A team of scientists from the UK Atomic Energy Authority, the Johannes Kepler University Linz, and Emmi AI, have developed an artificial intelligence tool - named GyroSwin - which can create simulations up to 1,000 times faster than traditional computational methods.

Magnetic nuclear fusion is considered a promising technology for sustainable and emission-free energy supply. However, to achieve fusion, machines need to confine plasma at extreme temperatures using powerful magnets. Managing turbulence within the plasma is a key fusion challenge so it needs to be accurately modelled.

Plasma scientists rely on state-of-the-art numerical simulations, using five-dimensional (5D) gyrokinetics, which includes three spatial dimensions plus two additional dimensions which account for parallel and perpendicular velocity of particles within the plasma. This 5D approach requires immense supercomputing power. Traditional simulations are extremely slow and computationally expensive, significantly lengthening design and development cycles. Previously, computation methods simulated a plasma by actively calculating the complex plasma dynamics.

GyroSwin uses the latest AI methods to learn the 5D simulation dynamics and the resulting surrogate models can run in seconds, in contrast to the hours or even days for conventional simulations. It was trained on six terabytes of data. This speed allows for much faster, more agile prediction of plasma turbulence, crucial for optimising fusion machine designs.

"Designing, developing, and operating a fusion power plant will involve millions of plasma simulations," said Rob Akers, Director of Computing Programmes at UKAEA. "Reducing runtimes from hours or days to minutes or seconds - whilst preserving sufficient accuracy - will be essential for making this challenge manageable. Pioneering AI-based tools like GyroSwin therefore show great promise for being genuinely transformative around time-to-solution and cost."

Processing 5D data has never previously been tackled by an AI surrogate model, and GyroSwin outperforms other AI methods it's been compared against, UKAEA noted. This increased performance is made possible because GyroSwin preserves key physical information from a fusion plasma, including the length scale of fluctuations, and the sheared flows that can reduce turbulence - all crucial to the physical interpretability of plasma simulations.

"We love scientific challenges, and building AI models that accelerate 5D gyrokinetic simulations is definitely one of the toughest challenges out there," said Johannes Brandstetter, Professor at JKU, co-founder and Chief Scientist at Emmi. "We are very proud of how far we got in this great collaboration, but we know that we have just scratched the surface."

UKAEA will now research how GyroSwin's advanced capability can be applied to next generation power plants such as the UK's Spherical Tokamak for Energy Production (STEP), where millions of simulations will potentially be required to optimise plasma scenario designs with uncertainty quantification. As more complex physics is included for power plant conditions, simulations become even more lengthy, making faster plasma modelling essential.This GyroSwin project was part-funded by the International Computing element of the UK Government's Fusion Futures Programme. AI tool can simulate complex fusion plasma in seconds
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New Ultrasonic Imaging System Can Detect Deadly Defects in All Types of Concrete

– credit Fujikawa et al. with background / SWNS

If a physician needs to see what’s gone wrong inside a human body, it’s easy enough to order an ultrasound scan. But if the structural engineer wants to do the same in a block of concrete, his options are of limited effectiveness.

The range of materials that concrete contains, such as stone, clay, chalk, slate, iron ore, and sand, scatters normal sound waves, making clear images difficult to obtain.

Now, Japanese and American scientists have teamed up to develop a system that can identify interior defects in concrete buildings and bridges without destroying their structure.

Team members explain in a news release that their method sends sound waves into the material and captures the waves that echo back to create images of what’s inside, just like an ultrasound.

“In our approach, the ultrasonic wave is broadband, using a wide range of ultrasonic frequencies rather than operating around a single, fixed frequency,” said Professor Yoshikazu Ohara from Tohoku University in Japan.

“The receiver is capable of accepting an even broader range of frequencies. By automatically adapting the frequency to the material, our system improves the contrast between defects and background material in concrete.”

Tohoku and his colleagues joined the Los Alamos National Laboratory in New Mexico, and Texas A&M University to create the system.

A chief challenge is that it’s hard to know which frequencies of sound waves will survive traveling through concrete, as different material therein may interfere with different wavelengths.

To accommodate the uncertainty, the team used two devices: one to generate a wide range of frequencies to send into the material and another, called a vibrometer, to capture the outcoming waves.

The system, described in the journal Applied Physics Letters, can handle a wide range of frequencies, which means that even if ultrasonic waves are scattered by materials in the concrete, those that do make it through are still detected, regardless of what frequency they are.

“As the concrete filters out certain frequencies, the laser Doppler vibrometer simply captures whatever frequencies remain,” said Professor Ohara. “Unlike conventional systems, we don’t have to swap transducers or adjust the frequency beforehand. The system adapts automatically.”

The result is a high-resolution 3D image of the defect and its location in the concrete.For a repair planner or field technician, this provides ‘concrete’ information: how deep the defect is from the surface, how large it is, and how it extends in three dimensions, making it possible to plan repairs more efficiently. New Ultrasonic Imaging System Can Detect Deadly Defects in All Types of Concrete
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Nanotechnology breakthrough may boost treatment for aggressive breast cancer: Study

IANS Photo

Sydney, (IANS): Researchers in Australia are developing next-generation nanoparticles to supercharge current treatments for triple-negative breast cancer (TNBC) -- one of the most aggressive and deadly forms of the disease.

The researchers are designing innovative iron-based nanoparticles, or "nano-adjuvants," small enough to fit thousands on a single strand of hair, to strengthen the body's immune response against TNBC, according to the University of Queensland's Australian Institute for Bioengineering and Nanotechnology (AIBN) on Monday, Xinhua news agency reported.

Unlike other breast cancers, TNBC lacks the proteins targeted by some of the conventional treatments used against other cancers, making effective therapy a significant challenge, according to Prof. Yu Chengzhong from the AIBN.

"Despite the promise of immunotherapy, its effectiveness against triple-negative breast cancer is extremely limited, which is leaving too many women without options -- and that's what our research is trying to change," Yu said.

The nanoparticles are designed to enhance the activity of T-cells, the white blood cells used by the immune system to fight disease, within the tumour microenvironment, improving the immune system's ability to recognise and attack cancer cells, according to Yu.

Supported by a 3 million Australian dollar ($1.89 million) National Health and Medical Research Council grant, the five-year research project aims to bridge a critical treatment gap, and could pave the way for clinical applications, not only for TNBC but also for other hard-to-treat cancers like ovarian cancer.

With over two decades of experience in nanotechnology and nanomedicine, Yu hopes this breakthrough will transform cancer treatment by making immunotherapy more effective for patients with aggressive solid tumours."This research will push the boundaries of science to find innovative treatments that change the way we fight this cancer, offering hope for women facing devastating outcomes," said AIBN Director Alan Rowan. Nanotechnology breakthrough may boost treatment for aggressive breast cancer: Study | MorungExpress | morungexpress.com
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ICRISAT develops portable technology for testing crops' nutrition level



The International Crops Research Institute for the Semi-Arid Tropics (ICRISAT) on Thursday announced that its researchers are leading a transformation in crop testing, combining AI-driven models and pocket-size near-infrared spectroscopy (NIRS) devices.

These portable sensors allow for quick evaluation of nutrition levels in indigenous food grains right at the farmer's gate or in research fields.

ICRISAT Director General, Dr Jacqueline d'Arros Hughes, championed the integration of this disruptive technology into breeding pipelines and key points of relevant value chains.

Aligned with the UN Food and Agriculture Organisation (FAO) strategy, she foresees the tool as a catalyst for the production of nutrient-dense crops, both in breeding programmes and in farmers' fields, a crucial element in the global fight against malnutrition.

"This technology is poised to expedite the breeding of nutrient-dense crops while facilitating their integration into the value chain. Our goal with this intervention is to provide quality assurance for the distribution of nutritionally fortified crops, so that they reach those who need them most," she added.

Traditionally, assessing the nutritional quality of grains and feedstock could take a number of weeks, involving manual or partially automated processes and laboratory instruments.

In contrast, mobile NIRS devices are more cost-effective and can assess over 150 samples per day per person, ICRISAT said.

These non-destructive and robust grain quality measuring devices provide timely information on grain composition and can be used to promote quality-based payments in the market—benefiting food producers, grain processing industries, and farmers alike.

"We see the adoption of portable technology for assessing grain quality as an important step in decentralising and democratising market systems, essential to promote the consumption of nutri-cereals. This transition can facilitate quality-driven payments for farmers, while providing quality assurance to health-conscious households moving forward," noted Dr Sean Mayes, Global Research Director of the Accelerated Crop Improvement Program at ICRISAT.

In Anantapur in Andhra Pradesh, ICRISAT recommends its Girnar 4 groundnut variety to ensure premium prices for farmers and to differentiate the crop from lower-value varieties. ICRISAT's Girnar 4 and Girnar 5 groundnut varieties boast oleic acid levels of 75-80 per cent, far surpassing that of the standard variety at 40-50 per cent.

Oleic acid is a heart-healthy monounsaturated fatty acid, which holds considerable importance for the groundnut market, as it provides new end-uses for the crop. Growing consumer awareness of its advantages spurred market demand for high oleic acid content in oils and related products.

This pioneering approach, initially applied in peanut breeding, could be replicated across other crops, offering efficient and cost-effective solutions to address poor nutrition.

ICRISAT's Facility for Exploratory Research on Nutrition (FERN laboratory) is expanding its prediction models to encompass various traits and crops beyond groundnuts."We are currently focusing on developing methods to assess oil, oleic acid, linoleic acid, carotenoids, starch, moisture, and phosphorus in various cereals and legumes, such as finger millet, foxtail millet, pearl millet, sorghum, maize, wheat, chickpea, mungbean, common bean, pigeon pea, cowpea, soybean, groundnut, and mustard," said Dr Jana Kholova, Cluster Leader. Crop Physiology and Modelling, ICRISAT. ICRISAT develops portable technology for testing crops' nutrition level | MorungExpress | morungexpress.com
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Cement Supercapacitors Could Turn the Concrete Around Us into Massive Energy Storage Systems

credit – MIT Sustainable Concrete Lab

Scientists from MIT have created a conductive “nanonetwork” inside a unique concrete mixture that could enable everyday structures like walls, sidewalks, and bridges to store and release electrical energy.

It’s perhaps the most ubiquitous man-made material on Earth by weight, but every square foot of it could, with the addition of some extra materials, power the world that it has grown to cover.

Known as e c-cubed (ec3) the electron-conductive carbon concrete is made by adding an ultra-fine paracrystalline form of carbon known as carbon black, with electrolytes and carbon nanoscales.

Not a new technology, MIT reported in 2023 that 45 cubic meters of ec3, roughly the amount of concrete used in a typical basement, could power the whole home, but advancements in materials sciences and manufacturing processes has improved the efficiency by orders of magnitude.

Now, just 5 cubic meters can do the job thanks to an improved electrolyte.

“A key to the sustainability of concrete is the development of ‘multifunctional concrete,’ which integrates functionalities like this energy storage, self-healing, and carbon sequestration,” said Admir Masic, lead author of the new study and associate professor of civil and environmental engineering at MIT.

“Concrete is already the world’s most-used construction material, so why not take advantage of that scale to create other benefits?”

The improved energy density was made possible by a deeper understanding of how the nanocarbon black network inside ec3 functions and interacts with electrolytes. Using focused ion beams for the sequential removal of thin layers of the ec3 material, followed by high-resolution imaging of each slice with a scanning electron microscope.

The team across the EC³ Hub and MIT Concrete Sustainability Hub was able to reconstruct the conductive nanonetwork at the highest resolution yet. This approach allowed the team to discover that the network is essentially a fractal-like “web” that surrounds ec3 pores, which is what allows the electrolyte to infiltrate and for current to flow through the system.

“Understanding how these materials ‘assemble’ themselves at the nanoscale is key to achieving these new functionalities,” adds Masic.

Equipped with their new understanding of the nanonetwork, the team experimented with different electrolytes and their concentrations to see how they impacted energy storage density. As Damian Stefaniuk, first author and EC³ Hub research scientist, highlights, “we found that there is a wide range of electrolytes that could be viable candidates for ec3. This even includes seawater, which could make this a good material for use in coastal and marine applications, perhaps as support structures for offshore wind farms.”

At the same time, the team streamlined the way they added electrolytes to the mix. Rather than curing ec3 electrodes and then soaking them in electrolyte, they added the electrolyte directly into the mixing water. Since electrolyte penetration was no longer a limitation, the team could cast thicker electrodes that stored more energy.

The team achieved the greatest performance when they switched to organic electrolytes, especially those that combined quaternary ammonium salts — found in everyday products like disinfectants — with acetonitrile, a clear, conductive liquid often used in industry. A cubic meter of this version of ec3—about the size of a refrigerator—can store over 2 kilowatt-hours of energy. That’s about enough to power an actual refrigerator for a day.

While batteries maintain a higher energy density, ec3 can in principle be incorporated directly into a wide range of architectural elements—from slabs and walls to domes and vaults—and last as long as the structure itself.

“The Ancient Romans made great advances in concrete construction. Massive structures like the Pantheon stand to this day without reinforcement. If we keep up their spirit of combining material science with architectural vision, we could be at the brink of a new architectural revolution with multifunctional concretes like ec3,” proposes Masic.

Taking inspiration from Roman architecture, the team built a miniature ec3 arch to show how structural form and energy storage can work together. Operating at 9 volts, the arch supported its own weight and additional load while powering an LED light.

The latest developments in ec³ technology bring it a step closer to real-world scalability. It’s already been used to heat sidewalk slabs in Sapporo, Japan, due to its thermally conductive properties, representing a potential alternative to salting.

“What excites us most is that we’ve taken a material as ancient as concrete and shown that it can do something entirely new,” says James Weaver, a co-author on the paper who is an associate professor of design technology and materials science and engineering at Cornell University, as well as a former EC³ Hub researcher. “By combining modern nanoscience with an ancient building block of civilization, we’re opening a door to infrastructure that doesn’t just support our lives, it powers them.” Cement Supercapacitors Could Turn the Concrete Around Us into Massive Energy Storage Systems
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TinyML: The Small Technology Tackling the Biggest Climate Challenge

Image by Gerd Altmann from Pixabay | For Representational Purpose Only

Tanveer Singh: As the planet struggles under the weight of 40+ billion metric tons of CO₂ emissions in 2024 alone, and an ever-rising energy demand, the search for smarter, leaner solutions has never been more urgent. There enters the TinyML, where the power of AI meets ultra-low energy computing to drive sustainability at scale.

It may be shocking, but as you are reading this, billions of sensors are tracking the planet’s health – from the air we breathe to the energy we consume. Already, more than 14 billion IoT devices are being used to monitor climate change and are projected to reach a whopping 30 billion by the end of 2030. But the concerning part is that the energy consumed by these devices is around 200 terawatt-hours of electricity annually, which is roughly equivalent to the entire energy consumption of countries like Thailand. To meet this demand, energy is produced through the traditional method of burning fuel, which further emits millions of Carbon footprints annually, that is even more than the lifetime emissions of 4 cars, just to monitor climate change. And therein lies the irony.

Furthermore, the constant transmission of data through these sensors requires millions of dollars for their deployment and maintenance. Like a large-scale smart city as big as New York, IoT networks can cost over $10–15 million per year to operate. This is exactly where TinyML comes as the solution, offering a path that enables IoT devices to process data locally, reducing energy consumption by up to 90% and significantly lowering costs.

Tiny ML bridges the gap between artificial intelligence and embedded systems, allowing machine learning activities even in sensors as small as a grain of sand. It is based on the idea of machine learning that is focused on building machine learning models on low-power devices like microcontrollers, enabling the device to process data instantly and anywhere, without depending on external internet storage to compute it. One clear example is Alexa, which uses TinyML models to send instant responses to the device for processing instead of sending through the cloud (external storage ), which will take a longer time.

Additionally, TinyML improves privacy and data security by running locally and reduces overall operational cost by 50-60% as compared to large ML models working on external storage. Take the example of Google's TinyML image classification that runs directly on devices, keeping images private while cutting storage and cloud costs by over 50%. TinyML can be best understood as having a mini robot in your pocket that can solve problems instantly, instead of always asking a big computer far away for help. It is faster, saves energy, and keeps your information private. When this field is applied to the climate, its efficiency becomes a distinguished factor.

Besides being cost-effective and having higher efficiency, it also helps in tracking air quality to predict natural disasters and, hence, supports the fight against climate change. Tiny ML sensors enable the quick detection of forest fires through heat or smoke detection, and aid in local air and water quality checks, eliminating the need for cloud computing dependency. For instance, Arduino-based air quality sensors are used to measure air quality and provide data on the temperature and humidity of an area. These models can also be used in solar or wind farms to check the performance of the solar cells and windmills through the consumption of energy, which can further help in increasing the efficiency of the farms. For example, Google’s DeepMind AI was successfully used with wind farms in the U.S. to predict wind power output 36 hours in advance, boosting the value of wind energy by around 20%. Interestingly, these sensors can also aid in monitoring birds' and whales' calls or other animals to track migration patterns and population health, as well as because of their small size and working on low power, and hence, they can help researchers to get valuable data on ecosystems without disturbing the wildlife. Moreover, TinyML sensors used in smart grids help in improving energy utilization by constantly monitoring and managing the transport of electricity so that energy is not wasted. Besides this, these devices can help in measuring the water pressure, tidal patterns, and ground movement of an area, and the data from this can be used to detect disasters earlier. For instance, in Japan, Tiny ML sensors placed along coastlines measure tidal waves and ground vibration in real time, which helps authorities to issue faster tsunami and earthquake warnings.

However, while these applications highlight the transformative impact of Tiny ML in tackling climate related problems, the integration also brings forth several challenges that need to be addressed to ensure reliability and scalability. First and foremost is the limitation of hardware, which is that there is limited storage, approximately in kilobytes or 1 to 5 megabytes, to store data compared to traditional models that have memory in gigabytes and terabytes. As a result, small models in TinyML will be less precise than the traditional models, which can be a huge challenge in models that work on reliability, for example, disaster management models. Furthermore, the harsh conditions like weather or wildlife can damage these devices, leading to malfunctioning and increasing the cost of maintenance.
Additionally, even though these devices are cost-effective, deploying billions of devices will still require huge funding, which can limit their production and scalability.

Despite these challenges, the future of TinyML is being shaped by the integration of emerging technologies, large-scale adoption, and the expanding market of AI. The combination of TinyML with the 5 G network, which provides 100 times faster speed than 4 G and the ability to connect over one million devices per square kilometer, can enable the creation of massive, interconnected sensors all over the cities that can provide faster and reliable data. Additionally, integrating it with federated learning- an ML technique that enables multiple devices to train a model together without sharing the raw data - can help in ensuring data privacy and increasing the accuracy of the models. Furthermore, Government and Research institutes are likely to adopt TinyML models in various tasks as they provide a scalable and cost-effective solution, especially in environments with limited resources. For instance, the U.S. National Aeronautics and Space Administration (NASA) has explored TinyML to process sensor data directly on satellites, reducing the need for constant communication with Earth.

It won’t be an exaggeration to say that the Tiny ML models have the potential to shape the future of the world. By offering scalable as well as energy-efficient solutions, Tiny ML stands out as the best alternative to tackle the climate change problems. From reducing the CO2 emissions to providing faster processing of data and strengthening the privacy and accuracy of the data, the Tiny ML model can be a changemaker catalyst not only in the world of climate change but in other fields, too. Undoubtedly, Tiny ML paves the way for a future where artificial intelligence works in harmony with the planet.Tanveer Singh, a first-year student at Plaksha University, has been passionate about writing articles and poems since high school. From raising public awareness of new technologies to highlighting environmental and societal issues, he has explored a wide range of themes through his work and aspires to continue making an impact in this space for the long run. TinyML: The Small Technology Tackling the Biggest Climate Challenge | MorungExpress | morungexpress.com
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Qualcomm drives digital future with AI, 6G and 'Make in India' initiatives

IANS Photo

New Delhi, (IANS): Qualcomm India is taking a leading role in shaping India’s digital future, emphasising its commitment to inclusive, sustainable, and globally competitive technology solutions, the tech giant said on Thursday.

At the India Mobile Congress (IMC) 2025, the company showcased a wide range of innovations, from Edge AI and 6G to smart homes, connected devices, and advanced compute platforms -- highlighting how its technologies are driving India’s digital transformation.

The company presented its vision for an intelligent and connected India through three pillars -- Personal AI, Physical AI, and Industrial AI -- reflecting Qualcomm’s focus on providing scalable, secure, and India-first solutions across consumer, enterprise, and infrastructure domains.

Qualcomm has been a long-time partner in India’s technology journey, supporting the country from 3G to 5G, while actively preparing for 6G through early-stage research, strategic partnerships, and local R&D investments.

At IMC 2025, Qualcomm highlighted the power of Edge AI combined with 5G as the twin pillars of India’s digital future.

Its platforms are enabling real-time, low-latency intelligence across industries, including automotive, industrial IoT, mobile devices, and compute solutions.

Demonstrations included on-device generative AI for smartphones and industrial devices, AI-powered surveillance, intelligent wearables like smartwatches and earbuds, and connected vehicles, all delivering seamless, multimodal experiences.

Savi Soin, Senior Vice President and President of Qualcomm India, said, “IMC 2025 reflects India’s strong digital momentum. Qualcomm is proud to lead with technologies that are cutting-edge and India-first, from Edge AI and 6G to smart homes and secure video solutions.”

The company also announced key collaborations with Indian partners to expand its ecosystem.

To nurture the next generation of AI talent in India, Qualcomm launched the Qualcomm AI Upskilling Programme: Technical Foundation, aimed at students, developers, and professionals. The program covers AI and ML fundamentals, Edge AI, generative AI, and practical experience with Qualcomm’s AI Hub, helping participants build on-device AI applications.

Through these initiatives, Qualcomm India is reinforcing its role as a digital transformation partner for the nation.By supporting Make in India, advancing 6G, enabling AI upskilling, and working closely with partners and policymakers, Qualcomm is contributing to an inclusive, innovative, and globally competitive digital future for India. Qualcomm drives digital future with AI, 6G and 'Make in India' initiatives | MorungExpress | morungexpress.com
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A Combination Implant and Augmented Reality Glasses Restores Reading Vision to Blind Eyes

Study participant Sheila Irvine training with the device – credit Moorfields Eye Hospital

A “new era” has begun in the development of artificial vision after a combination electronic eye implant—with augmented reality glasses restored vision to blind eyes in patients with untreatable macular degeneration.

Those treated with the device could read, on average, five lines of a vision chart, even though some could not even see the chart before their surgery.

The results of the European clinical trial which involved 38 patients in 17 hospitals across 5 countries were published in The New England Journal of Medicine. They showed 84% of participants were able to read letters, numbers, and words using prosthetic vision through an eye that had previously lost its sight due to the untreatable progressive eye condition, “geographic atrophy with dry age-related macular degeneration (GA in dry AMD).”

The now-proven device is called PRIMA, and consists of an ultra-thin microchip implanted in the eye that receives infrared projections of the waking world by a video camera installed in a pair of augmented reality classes.

A pocket computer fixed to a small control panel worn on the waistband then runs artificial intelligence algorithms to process the information contained in the infrared projection, which is converted into an electrical signal. This signal passes through the retinal and optical nerve cells into the brain, where it’s interpreted as vision.

The patient uses their glasses to focus and scan across the main object in the projected image from the video camera, using the zoom feature to enlarge the text. Each patient goes through an intensive rehabilitation program over several months to learn to interpret these signals and start reading again.

“In the history of artificial vision, this represents a new era,” said Mr. Mahi Muqit, associate professor at the UK’s University College London’s Institute of Ophthalmology and consultant at Moorfields Eye Hospital where the UK arm of the trial was conducted.

“Blind patients are actually able to have meaningful central vision restoration, which has never been done before.”

“Getting back the ability to read is a major improvement in their quality of life, lifts their mood and helps to restore their confidence and independence. The PRIMA chip operation can safely be performed by any trained vitreoretinal surgeon in under two hours—that is key for allowing all blind patients to have access to this new medical therapy for GA in dry AMD.”

Dry AMD is a slow deterioration of the cells of the macula over many years, as the light-sensitive retinal cells die off. For most people with dry AMD, they can experience a slight loss of central vision.

Through a process known as geographic atrophy (GA), it can progress to full vision loss in the eye, as the cells die and the central macula melts away. There is currently no treatment for GA, which affects 5 million people globally. All participants in this trial had lost the central sight of the eye being tested, leaving only limited peripheral vision.

Scans of the implant in a patient’s eye – credit Science Corporation

The procedure in install the implant involves a vitrectomy, where the eye’s vitreous jelly is removed from between the lens and the retina, and the surgeon inserts the ultra-thin microchip, which is shaped like a SIM card and just 2mm x 2mm.

The PRIMA System device used in this operation is being developed by Science Corporation, which develops brain-computer interfaces and neural engineering. No significant decline in existing peripheral vison was observed in trial participants, and these findings pave the way for seeking approval to market this new device.

UCL spoke with one of the patients who received the implant for the college’s news outlet.

“I wanted to take part in research to help future generations, and my optician suggested I get in touch with Moorfields,” began Sheila Irvine, one of Moorfields’ patients on the trial. “Before receiving the implant, it was like having two black discs in my eyes, with the outside distorted.

“I was an avid bookworm, and I wanted that back. I was nervous, excited, all those things. There was no pain during the operation, but you’re still aware of what’s happening. It’s a new way of looking through your eyes, and it was dead exciting when I began seeing a letter. It’s not simple, learning to read again, but the more hours I put in, the more I pick up.”

“The team at Moorfields has given me challenges, like ‘Look at your prescription,’ which is always tiny. I like stretching myself, trying to look at the little writing on tins, doing crosswords.”

The global trial was led by Dr. Frank Holz of the University of Bonn, with participants from the UK, France, Italy, and the Netherlands.

Mr. Muqit that it left him feeling that a door was opened for medical devices in this area, because there is no treatment currently licensed for dry AMD.“I think it’s something that, in future, could be used to treat multiple eye conditions.” A Combination Implant and Augmented Reality Glasses Restores Reading Vision to Blind Eyes
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First Light Fusion presents novel approach to fusion

(Image: First Light Fusion)

British inertial fusion energy developer First Light Fusion has presented the first commercially viable, reactor-compatible path to 'high gain' fusion, which it says would drastically reduce the cost of what the company says is a limitless clean energy source.

In its white paper published today, First Light Fusion (FLF) outlines a novel and scientifically grounded approach to fusion energy called FLARE – Fusion via Low-power Assembly and Rapid Excitation. While the conventional inertial fusion energy (IFE) approach is to compress and heat the fuel at the same time to achieve ignition, FLARE splits this process into two: first compressing the fuel in a controlled and highly efficient manner and then using a separate process to ignite the compressed fuel, generating a massive surplus of energy, a concept known as 'fast ignition'.

FLARE leverages over 14 years of First Light's inertial fusion experience and its unique controlled-amplification technology, creating a system capable of reaching the high gain levels needed for cost competitive energy production. This new approach "would underpin the design for commercial reactors that can be based on much lower power systems that already exist today, opening up an opportunity for partners to build those systems, using FLF's technology as the fuel, and to roll it out worldwide," according to the company.

Gain - the ratio of energy output to energy input in a fusion reaction – is the critical metric determining commercial viability. The current record gain level stands at 4, achieved at the US Department of Energy's National Ignition Facility (NIF) in May of this year.

"The FLARE concept, as detailed in today's white paper, could produce an energy gain of up to 1000. FLF's economic modelling suggests that a gain of at least 200 is needed for fusion energy to be commercially competitive, while a gain of 1000 would enable very low-cost power," the company said.

According to FLF, an experimental gain scale facility is expected to cost one-twentieth that of NIF and could be built using existing, proven technologies. Due to the lower energy and power requirements provided by the FLARE technology, future commercial power plants would have significantly lower capital costs than other plausible IFE schemes, with lower complexity and core components such as the energy delivery system costing one-tenth of the capital cost of previous fast ignition schemes.

"By building on existing technology, First Light's approach takes the brakes off inertial fusion deployment as it has the potential to leverage existing supply chains, significantly reduce capital expenditure, speed up planning approvals and reduce regulatory hurdles in the deployment of commercial fusion plants," it said.

"This is a pivotal moment not just for First Light, but for the future of energy," said First Light Fusion CEO Mark Thomas. "With the FLARE approach, we've laid out the world's first commercially viable, reactor-compatible pathway to high gain inertial fusion - and it's grounded in real science, proven technologies, and practical engineering.

"A pathway to a gain of 1000 puts us well beyond the threshold where fusion becomes economically transformative. Through our approach, we're opening the door to a new industrial sector - and we want to bring others with us."

First Light Fusion was founded by Yiannis Ventikos of the Mechanical Engineering Department at University College, London, and Nicholas Hawker, formerly an engineering lecturer at Lady Margaret Hall, Oxford. The company was spun out from the University of Oxford in July 2011, with seed capital from IP Group plc, Parkwalk Advisors Ltd and private investors. Invesco and OSI provided follow-on capital.In February, Oxfordshire-based First Light Fusion announced it will focus on commercial partnerships with other fusion companies who want to use its amplifier technology, as well as with non-fusion applications such as NASA seeking to replicate potential high-velocity impacts in space. By dropping its plans for a fusion power plant, and instead targeting commercial partnerships with others, it aims to "capitalise on the huge inertial fusion energy market opportunities enabling earlier revenues and lowering the long-term funding requirement". First Light Fusion presents novel approach to fusion
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GLE completes landmark laser technology demonstration

LEF facility (Image: GLE)

The large-scale enrichment technology testing campaign at Global Laser Enrichment's Test Loop facility in Wilmington, North Carolina, has demonstrated the commercial viability of laser enrichment.

Global Laser Enrichment (GLE) began the large-scale demonstration testing of the SILEX laser enrichment process in May. The extensive performance data it has collected provides confidence that the process can be commercially deployed, the company said. The demonstration programme will now continue through the rest of 2025, producing hundreds of kilograms of low-enriched uranium (LEU), while continuing towards building a domestic manufacturing base and supply chain to support deployment of US domestic enrichment capacity.

"We believe the enrichment activities conducted over the past five months position GLE to be the next American uranium enrichment solution," GLE CEO Stephen Long said, adding that, with 20% of US electricity supply coming from nuclear energy, this will "allow America to end its dangerous dependency on a fragile, foreign government-owned uranium fuel supply chain."

GLE is a joint venture of Australian company Silex Systems (51%) and Cameco Corporation (49%), and is the exclusive global licensee of the SILEX laser-based uranium enrichment technology invented by Silex Systems. Earlier this year, it completed the submission of an application to the US Nuclear Regulatory Commission for the Paducah Laser Enrichment Facility (PLEF) in Kentucky, where it plans to deploy the technology commercially, re-enriching depleted uranium tails from legacy Department of Energy gaseous diffusion plant operations.

The project is underpinned by a long-term agreement signed in 2016 for the sale to GLE of some 200,000 tonnes from the US Department of Energy's depleted uranium hexafluoride inventory, from which PLEF is expected to produce up to 6 million separative work units of LEU annually, delivering a domestic, single-site solution for uranium, conversion and enrichment, GLE completes landmark laser technology demonstration
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Scientists Regrow Retina Cells to Tackle Leading Cause of Blindness Using Nanotechnology


Macular degeneration is the leading cause of blindness in developed countries, but regrowing the human cells lost to this condition was the feature of a new successful treatment that took advantage of advances in nanotechnology.

Regrowing the cells of the human retina on a scaffold of synthetic, tissue-like material showed substantial improvements over previously used materials such as cellulose, and the scientists hope they can move on to testing their method in the already blind.

Macular degeneration is increasing in prevalence in the developed world. It’s the leading cause of blindness and is caused by the loss of cells in a key part of the eye called the retina.

Humans have no ability to regrow retinal pigment cells, but scientists have determined how to do it in vitro using pluripotent stem cells. However as the study authors describe, previous examples of this procedure saw scientists growing the cells on flat surfaces rather than one resembling the retinal membrane.

This, they state, limits the effectiveness of transplanted cells.

In a study at the UK’s Nottingham Trent University, biomedical scientist Biola Egbowon and colleagues fabricated 3D scaffolds with polymer nanofibers and coated them with a steroid to reduce inflammation.

The method by which the nanofibers were made was pretty darn cool. The team would squirt polyacrylonitrile and Jeffamine polymers in molten form through an electrical current in a technique known as “electrospinning.” The high voltage caused molecular changes in the polymers that saw them become solid again, resembling a scaffold of tiny fibers that attracted water yet maintained mechanical strength.

After the scaffolding was made, it was treated with an anti-inflammatory steroid.

This unique pairing of materials mixed with the electrospinning created a unique scaffold that kept the retinal pigment cells viable for 150 days outside of any potential human patient, all while showing the phenotype of biomarkers critical for maintaining retinal physiological characteristics.“While this may indicate the potential of such cellularized scaffolds in regenerative medicine, it does not address the question of biocompatibility with human tissue,” Egbowon and colleagues caution in their paper, urging more research to be conducted, specifically regarding the orientation of the cells and whether they can maintain good blood supply. Scientists Regrow Retina Cells to Tackle Leading Cause of Blindness Using Nanotechnology
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Scientists Develop Biodegradable Smart Textile–A Big Leap Forward for Eco-Friendly Wearable Technology

Flexible inkjet printed E-textile – Credit: Marzia Dulal

Wearable electronic textiles can be both sustainable and biodegradable, shows a new study.

A research team led by the University of Southampton and UWE Bristol in the UK tested a new sustainable approach for fully inkjet-printed, eco-friendly e-textiles.

Named SWEET—for Smart, Wearable, and Eco-friendly Electronic Textiles—the new ‘fabric’ was described in findings published in the journal Energy and Environmental Materials.


E-textiles are those with embedded electrical components, such as sensors, batteries or lights. They might be used in fashion, for performance sportswear, or for medical purposes as garments that monitor people’s vital signs.

Such textiles need to be durable, safe to wear and comfortable, but also, in an industry which is increasingly concerned with clothing waste, they need to be kind to the environment when no longer required.

“Integrating electrical components into conventional textiles complicates the recycling of the material because it often contains metals, such as silver, that don’t easily biodegrade,” explained Professor Nazmul Karim at the University of Southampton.


“Our eco-friendly approach for selecting sustainable materials and manufacturing overcomes this, enabling the fabric to decompose when it is disposed of.”

The team’s design has three layers, a sensing layer, a layer to interface with the sensors and a base fabric. It uses a textile called Tencel for the base, which is made from renewable wood and is biodegradable.

The active electronics in the design are made from graphene, along with a polymer called PEDOT: PSS. These conductive materials are precision inkjet-printed onto the fabric.

The research team, which included members from the universities of Exeter, Cambridge, Leeds, and Bath, tested samples of the material for continuous monitoring of heart rates. Five volunteers were connected to monitoring equipment, attached to gloves worn by the participants. Results confirmed the material can effectively and reliably measure both heart rate and temperature at the industry standard level.
Gloves with e-textile sensors monitoring heart rate – Credit: Marzia Dulal

“Achieving reliable, industry-standard monitoring with eco-friendly materials is a significant milestone,” said Dr. Shaila Afroj, an Associate Professor of Sustainable Materials from the University of Exeter and a co-author of the study. “It demonstrates that sustainability doesn’t have to come at the cost of functionality, especially in critical applications like healthcare.”


The project team then buried the e-textiles in soil to measure its biodegradable properties.

After four months, the fabric had lost 48 percent of its weight and 98 percent of its strength, suggesting relatively rapid and also effective decomposition.

Furthermore, a life cycle assessment revealed the graphene-based electrodes had up to 40 times less impact on the environment than standard electrodes.

Four strips in a variety of decomposed states, during four months of decomposition – Credit: Marzia Dulal

Marzia Dulal from UWE Bristol, the first author of the study, highlighted the environmental impact: “Our life cycle analysis shows that graphene-based e-textiles have a fraction of the environmental footprint compared to traditional electronics. This makes them a more responsible choice for industries looking to reduce their ecological impact.”

The ink-jet printing process is also a more sustainable approach for e-textile fabrications, depositing exact numbers of functional materials on textiles as needed, with almost no material waste and less use of water and energy than conventional screen printing.“These materials will become increasingly more important in our lives,” concluded Prof. Karim, who hopes to move forward with the team to design wearable garments made from SWEET, particularly in the area of early detection and prevention of heart diseases.Scientists Develop Biodegradable Smart Textile–A Big Leap Forward for Eco-Friendly Wearable Technology
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