Volcano on uninhabited Galapagos island spews lava

ECUADOR - A volcano on an uninhabited island of Ecuador's famous Galapagos archipelago is spewing lava, authorities said Sunday, potentially threatening an array of unique animal species. The La Cumbre volcano on the island of Fernandina blew its top late Saturday, the South American country's Geophysical Institute said. La Cumbre, which stands 1,463 meters (4,799 feet) high, has erupted three times previously since 2017. The Galapagos archipelago, some 1,000 kilometers (600 miles) off the mainland of Ecuador, has flora and fauna found nowhere else in the world. Observing its wonders led British scientist Charles Darwin to develop his ground-breaking theory of evolution by natural selection in the 19th century. La Cumbre has the highest eruption rate of all volcanos in the archipelago, which is a favorite with tourists. Fernandina, with no hotels or restaurants, can only be accessed for short visits from a cruise
GALAPAGOS NATIONAL PARK/AFP |
boat. The Institute said La Cumbre blew a gas cloud about three kilometers into the air, dispersed by the wind without passing over other islands with human settlements such as neighboring Isabela. It said the duration of the eruption cannot be predicted, nor whether the lava will reach the shore, but data on the volcano's activity suggested this one was likely to be greater than those in 2017, 2018 and 2020. The Institute advised tourists to stay away if any lava does enter the sea.sp/nn/mlr/mdl. Volcano on uninhabited Galapagos island spews lava
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Moderna CEO says melanoma vaccine could be available by 2025


WASHINGTON - Moderna CEO Stephane Bancel told AFP his company's experimental vaccine against melanoma could be available in as little as two years, in what would amount to a landmark step against the most serious form of skin cancer.

Globally there were an estimated 325,000 new melanoma cases and 57 ,000 deaths from the disease in 2020.

"We think that in some countries the product could be launched under accelerated approval by 2025," he said in an interview.


Unlike conventional vaccines, so-called therapeutic vaccines treat rather than prevent a disease. But they also work by training the body's own immune system against the invader.

Therapeutic vaccines today represent a real hope in oncology, an "immunotherapy 2.0," according to Bancel.

Moderna's aspirations received a boost Thursday with the latest clinical trial results showing an improvement over time in the chances of survival thanks to the vaccine, which uses the same messenger RNA technology that proved highly effective against serious forms of Covid-19.

In a study involving 157 people with advanced melanoma, the Moderna vaccine in combination with Merck's immunotherapy drug Keytruda reduced the risk of recurrence or death by 49 percent over a period of three years, compared with Keytruda alone.

Moderna had already announced two-year monitoring results last year, which showed a risk reduction of 44 percent.

"The difference in survival is growing. The more time passes, the more you see that advantage" said Bancel, noting that the rate of side effects hadn't increased.

"We have one in two people, compared to the best product on the market, who survive," he said, "which in oncology is huge."

- Seeking early approval -

The existing clinical evidence could thus form the basis for conditional approval of the vaccine, for now known as mRNA-4157, said Bancel.

Under this scenario, a larger, "phase three" study involving a thousand people that Moderna is carrying out in 2024 could confirm the earlier conditional authorization.

Both the US Food and Drug Administration and the European Medicines Agency have placed the therapy on an expedited review pathway.

The vaccine's development begins with sequencing the genome of each patient's tumor and identifying specific mutations to encode against. It is thus an example of "individualized" medicine tailored "just for you," said Bancel.

To prepare for market launch, Moderna is building a new factory in Massachusetts in order to have plentiful supply, a requirement of the FDA.

It also announced Monday that it was starting a phase 3 trial for an mRNA vaccine against lung cancer. Other types of tumors are also being studied.

Bancel's hope is to eventually pair these cancer vaccines with "liquid biopsies" -- groundbreaking tests that detect signs of tumors earlier, via blood tests, and are starting to become available in the United States.

The faster you can detect cancer, the better Moderna's new drugs will work, Bancel believes.

Other companies, such as BioNTech, are also working on individualized therapeutic cancer vaccines.

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Analyzing ways to help golden eagle populations weather wind-energy growth

"We are taking basic information about golden eagle ecology in the Anthropocene and developing it into predictive frameworks for how to protect them," says Eric Lonsdorf, Emory assistant professor of environmental sciences.
By Carol Clark: Wind energy is a major component of the U.S. clean-energy goals. Already one of the fastest growing and lowest-cost sources of electricity in the country, it is poised for even more rapid growth, according to the U.S. Department of Energy.

Wind power, however, does not come without trade-offs, including some negative impacts on wildlife. Throughout the United States, for example, it’s been estimated that as many as three golden eagles per wind farm are killed each year by wind turbines.

“Renewable energy sources, including wind energy, are critical for us to achieve a net-zero emissions future,” says Eric Lonsdorf, assistant professor of environmental sciences at Emory University. “We need to address conflicts between renewable energy and wildlife conservation so that we can combat climate change while also limiting damage to biodiversity.”

Lonsdorf and colleagues are developing data-driven methods to determine how much effort is needed to save golden eagles in order to offset the impact of wind turbines on their populations.

The Journal of Wildlife Management recently published their latest model for calculating the benefit of one mitigation strategy — removal of large, road-killed animals that can lead to golden eagles getting hit by cars.

Quantifying the benefits of natural capital:

Lonsdorf is an expert in natural capital, or the quantifiable benefits that nature provides humans. He translates ecological principles and data into computer models that enable industry leaders and policymakers to better manage natural resources.

Co-authors of the current study include James Gerber and Deepak Ray, from the University of Minnesota; Steven Slater, from HawkWatch International; and Taber Allison, from the Renewable Energy Wildlife Institute.

The U.S. Fish and Wildlife Service (FWS) monitors golden eagle populations, which are protected through the Bald and Golden Eagle Protection Act and the Migratory Bird Treaty Act. Threats to golden eagles include loss of habitat and prey.

Additional threats that are directly linked to human activities include illegal shootings, electrocution at power poles, lead poisoning from consuming parts of bullets in the entrails of deer carcasses discarded at the site of hunters’ kills, collisions with cars at sites where the birds are scavenging roadkill and collisions with the blades of a wind turbine.

Across the western United States, hundreds of wind turbines have gone up in sage-brush flats that are part of golden eagles’ core habitat, and many more turbines are planned. In order to meet the permit requirements of the FWS, wind-energy companies must agree to mitigate their impact on the animals by offsetting the predicted number of golden eagles that will fly into their turbines each year.

Currently, the only offset strategy approved by the FWS for wind-energy companies is to retrofit power poles to prevent golden eagles from becoming electrocuted.

Adding empirical data:

For the past five years, Lonsdorf and his colleagues have combined their expertise to develop a range of potential offset strategies for golden eagle fatalities.

Their current paper — an updated model for golden eagle mortality due to vehicle collisions based on data from Wyoming — considered myriad factors such as the population density for golden eagles in the region, the number and size of deer roadkill carcasses expected and the traffic volume on the roads. The model also incorporated observational evidence of eagle-carcass roadside interactions obtained by motion-triggered cameras, data that was lacking in a previous model the researchers created.

The addition of this empirical data allowed the researchers to make estimates for how long a golden eagle typically spends at a carcass, how the decay rate of the carcass affects the number of visits from eagles and the effects of seasonality on the scavenging behavior of the eagles.

The model results suggest that carcass relocation is a viable golden eagle mitigation strategy that could save up to seven golden eagles annually in some Wyoming counties. On average, the model indicates that the prompt removal of four roadside carcasses would save at least one golden eagle.

The researchers can make a user-friendly version of the prediction framework available to the FWS and wind-energy companies if the FWS decides to approve carcass removal as an eagle mortality offset strategy. “We’re taking basic information about golden eagle ecology in the Anthropocene and developing it into predictive frameworks for how to protect them,” Lonsdorf says. “As wind energy continues to grow, more mitigation strategies will likely be needed. Our goal is to provide scientific evidence for a portfolio of methods to help accomplish a zero-net loss of golden eagles from wind-energy facilities.”eScienceCommons: Analyzing ways to help golden eagle populations we
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Indian American scientist hoping to be first woman to jump from stratosphere

Swati Varshey has a PhD in materials science from the Massachusetts Institute of Technology and has made over 1,200 jumps with a speciality in vertical freefall, according to Space.com. Swati Varshney. PHOTO: @risingunited.org An Indian-American scientist is hoping to become the first woman to skydive from the stratosphere at an altitude of 42.5 km above the Earth, and shatter four records in the process. Swati Varshey has been selected as one of the three candidates selected by the Hera Project of Rising United that seeks to empower women in science and technology, the organization has announced. - If she makes it to the skydive in 2025, Hera Project expects her to break four current records: The free fall record by 1.1 kilometer from the highest altitude; endure the longest free fall time; break the sound barrier unaided by 264 kph; and the highest crewed balloon flight by over 1 kilometer. “At Rising United, we’re embarking on a historic journey, shattering records and ceilings to advance women’s equality and inspire young women’s interest in STEAM education”, the organization said. Swati Varshey has a PhD in materials science from the Massachusetts Institute of Technology and has made over 1,200 jumps with a specialty in vertical freefall, according to Space.com. Billed as the “First Female Mission to the Edge of Space”, the project seeks to have minority women smash the records, and the other two contenders are of Latino descent, Eliana Rodriquez and Diana Valerín Jiménez. The project will include educational programs for schools to increase interest in science and technology among girls, especially from minority groups. Varshney told Space.com that for her skydiving “is a lot more similar to my scientific training than I ever thought it would have been in the first place. It was just another avenue for me to pursue this goal of lifelong learning”. Varshney, who has spent a decade skydiving, told the media outlet, “My academic progression and my career trajectory has been really intertwined with skydiving as it went along. So I started skydiving”. She tried tandem jumping and found it such a “blast”, that she took it up as a hobby. “ I really just wanted something that was totally different, and as a release to — this is a really cliché way to say it — cut away right from what I was doing in my day-to-day life”, she told Space.com. “It became this never-ending journey of another pursuit of knowledge that went alongside my academic career”, she added. The stratosphere is from about 6 kilometers to 50 kilometers above the earth where it gives way to the mesosphere. Indian American scientist hoping to be first woman to jump from stratosphere:
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Why Should You Breastfeed Your Baby?

(Photo courtesy of Flushing Hospital Medical Center)
Flushing Hospital Medical Center’s New Beginnings unit provides the women and their families with the ultimate birthing experience. Each month, we cover a new topic exploring an important aspect of health and well-being for expectant mothers. This month, we’ll cover the health benefits of exclusive breastfeeding for both mothers and their babies. According to the American Academy of Pediatrics, exclusive breastfeeding involves only feeding breast milk to your baby and no other foods or liquids. It is the best source of nutrition for your infant’s first six months of life. 
Some of the benefits to babies and mothers include: 
  • Providing all necessary nutrients for the baby’s healthy physical development, including vitamin D, iron, and zinc
  • Preventing infections and serious health conditions, both during infancy and later in life
  • Reducing a mother’s risk of conditions such as cancer, type 2 diabetes, and high blood pressure
Breastfeeding may become less frequent as your baby starts eating solid foods around six to 12 months of age. For guidance on how you should breastfeed your baby, talk to a lactation consultant or your baby’s doctor or nurse.Flushing Hospital’s New Beginnings unit offers spacious, modern delivery suites and advanced postpartum care, providing you with a safe environment to give birth and comprehensive follow-up medical support for you and your baby. To learn more about the unit, including accommodations and services provided, please call us at Source: https://www.newsindiatimes.com/
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