Why your brain has to work harder in an open-plan office than private offices: study

Since the pandemic, offices around the world have quietly shrunk. Many organisations don’t need as much floor space or as many desks, given many staff now do a mix of hybrid work from home and the office.

But on days when more staff are required to be in, office spaces can feel noticeably busier and noisier. Despite so much focus on getting workers back into offices, there has been far less focus on the impacts of returning to open-plan workspaces.

Now, more research confirms what many suspected: our brains have to work harder in open-plan spaces than in private offices.

What the latest study tested

In a recently published study, researchers at a Spanish university fitted 26 people, aged in their mid-20s to mid-60s, with wireless electroencephalogram (EEG) headsets. EEG testing can measure how hard the brain is working by tracking electrical activity through sensors on the scalp.

Participants completed simulated office tasks, such as monitoring notifications, reading and responding to emails, and memorising and recalling lists of words.

Each participant was monitored while completing the tasks in two different settings: an open-plan workspace with colleagues nearby, and a small enclosed work “pod” with clear glazed panels on one side.

The researchers focused on the frontal regions of the brain, responsible for attention, concentration, and filtering out distractions. They measured different types of brain waves.

As neuroscientist Susan Hillier explains in more detail, different brain waves reveal distinct mental states:

  • “gamma” is linked with states or tasks that require more focused concentration
  • “beta” is linked with higher anxiety and more active states, with attention often directed externally
  • “alpha” is linked with being very relaxed, and passive attention (such as listening quietly but not engaging)
  • “theta” is linked with deep relaxation and inward focus
  • and “delta” is linked with deep sleep.

The Spanish study found that the same tasks done inside the enclosed pod vs the open-plan workspace produced completely opposite patterns.

It takes effort to filter out distractions

In the work pod, the study found beta waves – associated with active mental processing – dropped significantly over the experiment, as did alpha waves linked to passive attention and overall activity in the frontal brain regions.

This meant people’s brains needed progressively less effort to sustain the same work.

The open-plan office testing showed the reverse.

Gamma waves, linked to complex mental processing, climbed steadily. Theta waves, which track both working memory and mental fatigue, increased. Two key measures also rose significantly: arousal (how alert and activated the brain is) and engagement (how much mental effort is being applied).

In other words, in the open-plan office participants’ brains had to work harder to maintain performance.

Even when we try to ignore distractions, our brain has to expend mental effort to filter them out.

In contrast, the pod eliminated most background noise and visual disruptions, allowing participant’s brains to work more efficiently.

Researchers also found much wider variability in the open office. Some people’s brain activity increased dramatically, while others showed modest changes. This suggests individual differences in how distracting we find open-plan spaces.

With only 26 participants, this was a relatively small study. But its findings echo a significant body of research from the past decade.

What past research has shown

In our 2021 study, my colleagues and I found a significant causal relationship between open-plan office noise and physiological stress. Studying 43 participants in controlled conditions – using heart rate, skin conductivity and AI facial emotion recognition – we found negative mood in open plan offices increased by 25% and physiological stress by 34%.

Another study showed background conversations and noisy environments can degrade cognitive task performance and increase distraction for workers.

And a 2013 analysis of more than 42,000 office workers in the United States, Finland, Canada and Australia found those in open-plan offices were less satisfied with their work environment than those in private offices. This was largely due to increased, uncontrollable noise and lack of privacy.

Just as we now recognise poorly designed chairs cause physical strain, years of research has shown how workspace design can result in cognitive strain.

What to do about it

The ability to focus and concentrate without interruption and distraction is a fundamental requirement for modern knowledge work.

Yet the value of uninterrupted work continues to be undervalued in workplace design.

Creating zones where workers can match their workplace environment to the task is essential.

Responding to having more staff doing hybrid work post-pandemic, LinkedIn redesigned its flagship San Francisco office. LinkedIn halved the number of workstations in open plan areas, instead experimenting with 75 types of work settings, including work areas for quiet focus.

For organisations looking to look after their workers’ brains, there are practical measures to consider. These include setting up different work zones, acoustic treatments and sound-masking technologies, and thoughtfully placed partitions to reduce visual and auditory distractions.

While adding those extra features in may cost more upfront than an open plan office, they can be worth it. Research has shown the significant hidden toll of poor office design on productivity, health and employee retention.

Providing workers with more choice in how much they’re exposed to noise and other interruptions is not a luxury. To get more done, with less strain on our brains, better design at work should be seen as a necessity.The Conversation

Libby (Elizabeth) Sander, MBA Director & Associate Professor of Organisational Behaviour, Bond Business School, Bond University

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Researchers Discover New Mechanism for Rapid Liver Regeneration to Restore Damaged Livers

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Researchers at the National Cancer Research Centre in Spain (CNIO) have discovered a mechanism that is triggered just minutes after acute liver damage occurs—and it could lead to treatments for those with severe liver problems.

The avenues for future treatments of liver damage include a diet enriched with the amino acid glutamate.

“Glutamate supplementation can promote liver regeneration and benefit patients in recovery following hepatectomy or awaiting a transplant,” wrote the authors in a paper published in ‘Nature’.

The liver is a vital organ, crucial to digestion, metabolism, and the elimination of toxins. It has a unique ability to regenerate, which allows it to replace liver cells damaged by the very toxins that these cells eliminate.

However, the liver stops regenerating in cases of diseases that involve chronic liver damage–such as cirrhosis—and such diseases are becoming increasingly prevalent, associated with poor dietary habits or alcohol consumption. So activating liver regeneration is key to treating the disease.

Learning to activate liver regeneration is therefore a priority today, to benefit patients with liver damage and also those who’ve had part of their liver cut out to remove a tumor.

The research has discovered in animal models this previously unknown mechanism of liver regeneration. It is a process that is triggered very quickly, just a few minutes after acute liver damage occurs, with the amino acid glutamate playing a key role.

“Our results describe a fundamental and universal mechanism that allows the liver to regenerate after acute damage,” explained Nabil Djouder, head of the CNIO Growth Factors, Nutrients and Cancer Group and senior author of the study.

A “complex and ingenious” perspective on liver regeneration

Liver regeneration was known to occur through the proliferation of liver cells, known as hepatocytes. However, the molecular mechanisms involved were not fully understood. This current discovery is very novel, as it describes communication between two different organs, the liver and bone marrow, involving the immune system, according to a CINO news release.

The results show that liver and bone marrow are interconnected by glutamate. After acute liver damage, liver cells, called hepatocytes, produce glutamate and send it into the bloodstream; through the blood, glutamate reaches the bone marrow, inside the bones, where it activates monocytes, a type of immune system cell. Monocytes then travel to the liver and along the way become macrophages – also immune cells. The presence of glutamate reprograms the metabolism of macrophages, and these consequently begin to secrete a growth factor that leads to an increase in hepatocyte production.

In other words, a rapid chain of events allows glutamate to trigger liver regeneration in just minutes, through changes in the macrophage metabolism. It is, says Djouder, “a new, complex and ingenious perspective on how the liver stimulates its own regeneration.”

The research also clarifies a previously unanswered question: how the various areas of the liver are coordinated during regeneration. In the liver, there are different types of hepatocytes, organized in different areas; the hepatocytes in each area perform specific metabolic functions. The study reveals that hepatocytes producing a protein known as glutamine synthetase, which regulates glutamate levels, play a key role in regeneration.

According to the CNIO group, when glutamine synthetase is inhibited, there is more glutamate in circulation, which accelerates liver regeneration. This is what happens when the liver suffers acute damage: glutamine synthase activity decreases, blood glutamate increases, and from there, the connection with the bone marrow is established, reprogramming macrophages and stimulating hepatocyte proliferation.
Possible therapeutic applications

The experiments have been carried out in mice, but the results have been tested with bioinformatics tools, using databases of mouse and human hepatocytes.

According to Djouder, “dietary glutamate supplementation may simply be recommended in the future after liver extirpation, and also to reduce liver damage caused by cirrhosis.”

The first author of the paper, CNIO researcher María del Mar Rigual also wants future research to explore using glutamate supplements in humans who have undergone liver resection for tumor removal. Researchers Discover New Mechanism for Rapid Liver Regeneration to Restore Damaged Livers
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