Bobi, known as the oldest dog in the world, dies aged 31

Bobi, who was this year ordained the oldest dog in the world by Guinness World Records, has died at the ripe old age of 31, Portuguese media reported Monday.

"We have better memories of a long life where he was happy and, above all, where he made a lot of people happy, especially his family," Bobi's owner Leonel Costa told local media from the little village in central Portugal where he lives.

A purebreed Rafeiro, a Portuguese livestock guard dog whose normal life expectancy is between 12 and 14, Bobi was not supposed to make it beyond puppyhood.

He was born on May 11, 1992, along with three other pups in a wood storage shed owned by the Costa family in the village of Conqueiros.

Because the family owned so many animals, the father decided they could not keep the newborn puppies and the parents took them from the shed the next day, while the mother dog Gira was out, said Leonel Costa, who was eight years old at the time.

But they didn't realise they had left one puppy behind, and that puppy became Bobi.

"He died at the age of 31 years and 165 days," according to the Guinness World Records.After he was declared the world's oldest dog in February, media and curious onlookers from around the world paid Bobi a visit. Bobi, known as the oldest dog in the world, dies aged 31
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Telomere lengthening via gene therapy achieved for the first time

U.S. biotech company BioViva has announced the first successful use of gene therapy to extend telomeres, believed to be vitally important in the fight against human aging.
In September 2015, then 44 year-old CEO of BioViva, Elizabeth Parrish, received two of her own company's experimental gene therapies: one to protect against loss of muscle mass with age; another to battle stem cell depletion responsible for diverse age-related diseases and infirmities.

The treatment was originally intended to demonstrate the safety of the latest generation of the therapies. But if early data is accurate, it is already the world's first successful example of telomere lengthening via gene therapy in a human individual. Gene therapy has been used to lengthen telomeres before in mice and in cultured cells – but never in a human patient, until now.

Telomeres are short segments of DNA which cap the ends of every chromosome. Like the plastic tips on shoelaces that stop them from fraying, they act as 'buffers' against wear and tear. With every cell division they become shorter, eventually getting too short to protect the chromosome, causing the cell to malfunction and the body to age.

In September 2015, telomere data from Parrish's white blood cells (immediately before therapies were administered), revealed that her telomeres were unusually short for her age, leaving her vulnerable to age-related diseases earlier in life.

In March 2016, following BioViva's treatment, the same tests taken again revealed that her telomeres had lengthened by the equivalent of 20 years, from 6.71kb to 7.33kb – implying that Parrish's white blood cells (leukocytes) had become biologically younger. These findings were independently verified by the non-profit, Brussels-based HEALES (HEalthy Life Extension Company), and the Biogerontology Research Foundation, a UK-based charity committed to aging research.

"Current therapeutics offer only marginal benefits for people suffering from diseases of aging," Parrish commented. "Additionally, lifestyle modification has limited impact for treating these diseases. Advances in biotechnology are the best solution, and if these results are anywhere near accurate, then we've made history."

BioViva will continue to monitor Parrish's blood for months and years to come. Meanwhile, the company will be testing new gene therapies and combination gene therapies to restore age-related damage. It remains to be seen whether the success in leukocytes can be expanded to other tissues and organs, and repeated in future patients with larger sample sizes. For now, all the answers lie in the cells of Elizabeth Parrish, "patient zero" of restorative gene therapy.

Since her first gene therapy injections, BioViva has received global interest from both the scientific and investment communities. Earlier this month, BioViva became a portfolio company of Deep Knowledge Life Sciences (DKLS), a London-based investment fund which aims to accelerate the development of biotechnologies for healthy longevity.

Dmitry Kaminskiy, founding partner of DKLS, said: "Many innovative companies have come to us looking for funding and support. BioViva is one among several other breakthrough companies that are going to leapfrog the current generation of biotech and will be included in our portfolio. This is the start of a big trend, and it ought to give investors food for thought. 2017 will be the year in which we will see an investment boom in the longevity industry."Source: http://www.futuretimeline.net/
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The world's first nation state in space

Credit: Asgardia
At a press conference in Paris this week, plans were announced for the creation of 'Asgardia' – the first nation state in outer space.

Named after the city of the skies in Norse mythology, Asgardia is a space-based nation proposed by Dr Igor Ashurbeyli, founder of the Aerospace International Research Centre (Vienna), and Chairman of UNESCO's Science of Space committee. The concept is aimed at creating a new framework for how space activities are regulated and owned, ensuring that "the future of space is peaceful and done for the benefit of humankind."

Dr Ashurbeyli, one of the Russian Federation's most distinguished scientists, has consulted globally renowned scientists, engineers, entrepreneurs and legal experts on the development of the concept. The project's official website is currently requesting people to register for "citizenship" with the aim of applying to the United Nations for official recognition as a nation state. Already, hundreds of thousands have signed up.

As a first step, the organisation plans to crowd-source a satellite for launch in 2017, sixty years after Sputnik 1, the first ever satellite. This will mark a new era in the space age, the organisation claims, as the satellite will be independent of any current nation state on Earth: the satellite will comprise the nation itself – creating its own legal system, flag and other symbols of nationhood.

"The project's concept comprises three parts – philosophical, legal and scientific/technological," Dr Ashburbeyli explained. "Asgardia is a fully-fledged and independent nation, and a future member of the United Nations – with all the attributes this status entails. The essence of Asgardia is 'Peace in Space', and the prevention of Earth's conflicts being transferred into space.

"Asgardia is also unique from a philosophical aspect: to serve entire humanity and each and everyone, regardless of his or her personal welfare and the prosperity of the country where they happened to be born. The scientific and technological component of the project can be explained in just three words – peace, access and protection. The scientific and technological envelope of Asgardia is a space arena for the scientific creativity of its citizens and companies in developing a broad range of future space technologies, products and services for humanity on Earth and humanity in space."


In recent years, access to space has been opening up, but the process remains slow and is tightly controlled by states on Earth, restricting commerce and scientific developments by private enterprise. Of the 196 nation states, just thirteen (China, France, India, Iran, Israel, Japan, North Korea, Russia/former USSR, South Korea, UK, Ukraine, USA) and one regional organisation (the European Space Agency, ESA) have independently launched satellites on their own indigenously developed launch vehicles.

Professor David Alexander, Director of the Rice Space Institute at Rice University in Texas: "As low-Earth orbit becomes more accessible, what's often called the 'democratisation' of space, a pathway is opening up to new ideas and approaches from a rich diversity of participants. The mission of Asgardia to create opportunities for broader access to space, enabling non-traditional space nations to realise their scientific aspirations is exciting."

Under current international space law, including the widely adopted Outer Space Treaty, states are required to authorise and supervise national space activities, including the activities of commercial and not-for-profit organisations. Objects launched into space are subject to their nation of belonging and if a nation launches an object into space, that nation is responsible for any damage that occurs internationally and in outer space.

Asgardia aims to create a new framework for ownership and nationhood in space, adapting current laws governing responsibility, private ownership and enterprise so they are fit for purpose in the new era of space exploration. By creating a new "space nation", private enterprise, innovation and the further development of space technology to support humanity could flourish, free from the tight restrictions of state control that currently exist.

Professor Ram Jakhu, Director, Institute of Air and Space Law at McGill University, Montreal, Canada: "An appropriate and unique global space legal regime is indispensable for governing outer space in order to ensure it is explored on a sustainable basis, for exclusively peaceful purposes and to the benefit of all humanity – including future generations living on planet Earth and in outer space. The development of foundational principles of such a legal regime ought to take place at the same time as technological progress is being made."


One of the early developments planned by Asgardia's team will be the creation of a state-of-the-art protective shield for all humankind from cosmic manmade and natural threats to life on Earth such as space debris, coronal mass ejections and asteroid collisions.

There are estimated to be more than 20,000 traceable objects of man-made space debris (MSD) including non-active spacecraft, upper-stage rockets and final stage vehicles, as well as fragments of craft that potentially pose a danger in near-Earth orbits. The impact of the Chelyabinsk meteorite which crashed over a Russian town as recently as 2013, injuring 1,100 people and damaging 4,000 buildings, is a reminder of the threat that natural objects pose to life on our planet.

Whilst steps have already been taken by the UN and the Space Mission Planning Advisory Group (SMPAG) to identify potentially hazardous scenarios, Asgardia will build on these developments to offer a more comprehensive mechanism.

Dr. Joseph N. Pelton, former Dean of the International Space University in Strasbourg, France: "The Asgardia project, among other things, may help prepare better answers to the future governance of outer space – a topic of major concern to the United Nations. The exciting aspect of this initiative is its three phase approach to providing broader access to space; promoting peace in outer space; and addressing cosmic hazards and planetary defence."

The Asgardia Project Team will comprise a collaborative, multi-disciplinary effort from leading experts around the globe which it is envisaged will grow over time as the project evolves. But as well as expert involvement in the project, Asgardia is looking to capture the wider public imagination by crowd-sourcing key aspects of the missions and involving members of the public in competitions – for example, to help design the nation's flag, insignia and other symbols of nationhood.

To coincide with the press conference, a website with further details was launched at www.asgardia.space. The project can also be followed on Twitter where updates will be provided, along with interaction between the Asgardia team and members of the public. ---Source: http://www.futuretimeline.net/
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China launches spacecraft in longest-ever manned mission

The Shenzhou 11 astronauts are Jing Haipeng, who is flying his third mission, and 37-year-old Chen Dong.
The Shenzhou 11 mission took off from the Jiuquan Satellite Launch Center on the edge of the Gobi Desert in northern China. China launched a pair of astronauts into space Monday on a mission to dock with an experimental space station and remain aboard for 30 days in preparation for the start of operations by a full-bore facility six years from now. The Shenzhou 11 mission took off from the Jiuquan Satellite Launch Center on the edge of the Gobi Desert in northern China at 7:30 a.m. (2330 GMT) aboard a Long March-2F carrier rocket. It will dock with the Tiangong 2 space station precursor facility within two days, conduct experiments in medicine and various space-related technologies, and test systems and processes in preparation for the launching of the station's core module in 2018. Space program commander-in-chief Gen. Zhang Youxia declared the launch a success at 7:46 a.m. (2346 GMT). Defense Minister Fan Changlong then read a congratulatory message from President Xi Jinping calling for China's astronauts to explore space "more deeply and more broadly." Premier Li Keqiang and propaganda chief Liu Yunshan visited the Beijing control center to congratulate staff. It is the sixth time
China has launched astronauts into space and the duration will be the longest by far. Following the attachment of two experiment modules, the completed station is set to begin full operations in 2022 and will run for at least a decade. An earlier Tiangong 1 experimental space station launched in 2011 went out of service in March after docking with three visiting spacecraft and extending its mission for two years. The Tiangong, or "Heavenly Palace," stations are considered stepping stones to a mission to Mars by the end of the decade. The Shenzhou 11 astronauts are Jing Haipeng, who is flying his third mission, and 37-year-old Chen Dong. "It is any astronaut's dream and pursuit to be able to perform many space missions," Jing, who turns 50 during his time in space, told a briefing Sunday. China conducted its first crewed space mission in 2003, becoming only the third country after Russia and the U.S. to do so, and has since staged a spacewalk and landed its Yutu rover on the moon. Administrators suggest a crewed landing on the moon may also be in the program's future. China was prevented from participating in the International Space Station, mainly due to US concerns over the Chinese space program's strongly military character. Chinese officials are now looking to internationalize their own program by offering to help finance other countries' missions to Tiangong 2. China's space program also opened its massive fourth spacecraft launch site at Wenchang on China's southernmost island province of Hainan in June. It was inaugurated with the launch of the newly developed Long March 7 rocket that was hailed as a breakthrough in the use of safer, more environmentally friendly fuels. China is currently developing the Long March 5 heavy-lift rocket needed to launch the Tiangong 2's additional components and other massive payloads. China also plans to land a rover on Mars by 2020, attempting to recreate the success of the US Viking 1 mission that landed a rover on the planet four decades ago. A source of enormous national pride, China's space program plans a total of 20 missions. (This story first appeared in Deccan Chronicle) Source: The Asian Age
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First detection of super-Earth atmosphere

Credit: ESA/Hubble, M. Kornmesser
NASA's Hubble Space Telescope has detected hydrogen and helium, but no water vapour, in the atmosphere of 55 Cancri e – the first time the atmosphere of a "super-Earth" has been analysed successfully. For the first time, astronomers were able to analyse the atmosphere of an exoplanet in the class known as super-Earths. Using data gathered with the NASA/ESA Hubble Space Telescope and new analysis techniques, the exoplanet 55 Cancri e is revealed to have a dry atmosphere without any indications of water vapour. The results, to be published in the Astrophysical Journal, indicate that the atmosphere consists mainly of hydrogen and helium. The international team, led by scientists from University College London (UCL), took measurements of the nearby exoplanet 55 Cancri e, a super-Earth with a mass of eight Earths. It is located in the planetary system of 55 Cancri, a star about 40 light-years from Earth. Using observations made by the Wide Field Camera 3 (WFC3) on board the NASA/ESA Hubble Space Telescope, the scientists were able to analyse the atmosphere in detail. The results were only made possible by exploiting a newly-developed processing technique. "This is a very exciting result,
because it's the first time that we have been able to find the spectral fingerprints that show the gases present in the atmosphere of a super-Earth," explains Angelos Tsiaras, a PhD student at UCL, who developed the analysing technique, along with his colleagues Ingo Waldmann and Marco Rocchetto. "The observations of 55 Cancri e's atmosphere suggest that the planet has managed to cling on to a significant amount of hydrogen and helium from the nebula from which it originally formed." Super-Earths like 55 Cancri e are thought to be the most common type of planet in our galaxy. They acquired the name 'super-Earth' because they have a mass larger than that of the Earth, but are still much smaller than the gas giants in the Solar System. The WFC3 instrument on Hubble has already been used to probe the atmospheres of two other super-Earths, but no spectral features were found in those previous studies. 55 Cancri e, however, is an unusual super-Earth, as it orbits very close to its parent star. A year on the exoplanet lasts for only 18 hours and temperatures on the surface are thought to reach around 2000 degrees Celsius. Because the planet orbits its bright parent star at such a small distance, the team was able to use their new technique to extract key information about the planet, during its transits in front of the host star. Observations were made by scanning the WFC3 very quickly across the star to create a number of spectra. By combining these observations and processing them through analytic software, the researchers were able to retrieve the spectrum of 55 Cancri e embedded in the light of its parent star. "This result gives a first insight into the atmosphere of a super-Earth. We now have clues as to what the planet is currently like and how it might have formed and evolved, and this has important implications for 55 Cancri e and other super-Earths," said Giovanna Tinetti, also from UCL. Intriguingly, the data also contain hints of the presence of hydrogen cyanide, a marker for carbon-rich atmospheres. "Such an amount of hydrogen cyanide would indicate an atmosphere with a very high ratio of carbon to oxygen," said Olivia Venot, KU Leuven, who developed an atmospheric chemical model of 55 Cancri e that supported the analysis of the observations. "If the presence of hydrogen cyanide and other molecules is confirmed in a few years time by the next generation of infrared telescopes, it would support the theory that this planet is indeed carbon rich and a very exotic place," concludes Jonathan Tennyson, UCL. "Although hydrogen cyanide, or prussic acid, is highly poisonous, so it is perhaps not a planet I would like to live on!"Source: http://www.futuretimeline.net/
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